• Deletion of the GI-2 integrase and the wbkA flanking transposase improves the stability of Brucella melitensis Rev 1 vaccine 

      Mancilla, Marcos; Grilló Dolset, María Jesús; Miguel López, María Jesús de; López Goñi, Ignacio; San Román Aberasturi, Beatriz Upna; Zabalza Baranguá, Ana Upna; Moriyón Uría, Ignacio (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Brucella melitensis Rev 1 is the best vaccine available for the prophylaxis of small ruminant brucellosis and, indirectly, for reducing human brucellosis. However, Rev 1 shows anomalously high rates of spontaneous dissociation ...
    • The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice 

      San Román Aberasturi, Beatriz Upna; Lasa Uzcudun, Íñigo Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria Upna; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña Upna; Andrés, Ximena de; Zabaleta, Virginia Upna; Mansilla, Cristina; Farrán Blanch, Inmaculada Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
    • Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice 

      Soler Lloréns, Pedro; Gil Ramírez, Yolanda Upna; Zabalza Baranguá, Ana Upna; Iriarte, Maite; Conde Álvarez, Raquel; Zúñiga Ripa, Amaia; San Román Aberasturi, Beatriz Upna; Zygmunt, Michel; Vizcaíno, Nieves; Cloeckaert, Axel; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; López Goñi, Ignacio (BioMed Central, 2014)   Artículo / Artikulua  OpenAccess
      Brucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ...
    • Sensitivity of the ISO 6579:2002/Amd 1:2007 standard method for detection of Salmonella spp. on mesenteric lymph nodes from slaughter pigs 

      Mainar Jaime, Raúl Carlos; Andrés, S.; Vico, J. P.; San Román Aberasturi, Beatriz Upna; Garrido, Victoria Upna; Grilló Dolset, María Jesús (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The ISO 6579:2002/Amd 1:2007 (ISO) standard has been the bacteriological standard method used in the European Union for the detection of Salmonella spp. in pig mesenteric lymph nodes (MLN), but there are no published ...
    • Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs 

      Garrido, Victoria Upna; Sánchez Alarcón, Samanta Rita; San Román Aberasturi, Beatriz Upna; Zabalza Baranguá, Ana Upna; Díaz Tendero, Yasmín; Frutos, Cristina de; Mainar Jaime, Raúl Carlos; Grilló Dolset, María Jesús (BioMed Central, 2014)   Artículo / Artikulua  OpenAccess
      Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis ...
    • Situación epidemiológica y sanitaria de la salmonelosis porcina en la C.F. de Navarra y contribución al conocimiento de la patogénesis 

      Sánchez Alarcón, Samanta Rita (2015)   Tesis doctoral / Doktoretza tesia  OpenAccess
      El objetivo general de esta tesis doctoral fue analizar la situación epidemiológica y sanitaria de las infecciones por Salmonella spp. en una población representativa del ganado porcino de cebo y en cerdas reproductoras ...
    • Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Bertolotti, Luigi; Cenoz, Amaia Upna; Hernández, Mirna Margarita; San Román Aberasturi, Beatriz Upna; Glaría Ezquer, Idoia Upna; Andrés, Ximena de; Crespo, Helena Upna; Jauregui, Paula; Benavides, Julio; Polledo, Laura; Pérez, Valentín; García Marín, Juan F.; Rosati, Sergio; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...