Browsing by UPNA Author "Barajas Vélez, Miguel Ángel"
Now showing items 1-16 of 16
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Antidiabetic effects of Pediococcus acidilactici pA1c on HFD-induced mice
Prediabetes (PreD), which is associated with impaired glucose tolerance and fasting blood glucose, is a potential risk factor for type 2 diabetes mellitus (T2D). Growing evidence suggests the role of the gastrointestinal ... -
Chemically defined conditions mediate an efficient induction of dental pulp pluripotent-like stem cells into hepatocyte-like cells
Liver diseases are major causes of morbidity and mortality. Dental pulp pluripotent-like stem cells (DPPSCs) are of a considerable promise in tissue engineering and regenerative medicine as a new source of tissue-specific ... -
A combination of apple vinegar drink with Bacillus coagulans ameliorates high fat diet-induced body weight gain, insulin resistance and hepatic steatosis
Obesity is a worldwide epidemic characterized by excessive fat accumulation, associated with multiple comorbidities and complications. Emerging evidence points to gut microbiome as a driving force in the pathogenesis of ... -
Comparison of 0.12% chlorhexidine and a new bone bioactive liquid, BBL, in mouthwash for oral wound healing: a randomized, double blind clinical human trial
Following surgery, healing within the oral cavity occurs in a hostile environment, and proper oral care and hygiene are required to accelerate recovery. The aim of the current study is to investigate and compare the ... -
Elovanoids counteract inflammatory signaling, autophagy, endoplasmic reticulum stress, and eenescence gene programming in human nasal epithelial cells exposed to allergens
To contribute to further understanding the cellular and molecular complexities of inflammatory-immune responses in allergic disorders, we have tested the pro-homeostatic elovanoids (ELV) in human nasal epithelial cells ... -
Experimental pilot study after surgery on a food supplement for athletes to protect articular knee cartilage. A functional and biochemical study
En este estudio experimental doble ciego se evalúa la eficacia de la suplementación condroprotectora (Carticure Plus®, 5000 mg Colágeno (Péptidos Bioactivos) altamente asimilable, 1500 mg Glucosamina clorhidrato, 1200 mg ... -
A fermented food product containing lactic acid bacteria protects ZDF rats from the development of type 2 diabetes
Type 2 diabetes (T2D) is a complex metabolic disease, which involves a maintained hyperglycemia due to the development of an insulin resistance process. Among multiple risk factors, host intestinal microbiota has received ... -
Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue
In this work, mesenchymal stem cells derived from adipose tissue (ADSCs) were used for the generation of the human-induced pluripotent stem cell line G15.AO. Cell reprogramming was performed using retroviral vectors ... -
Histologic and histomorphometric evaluation of a new bioactive liquid bbl on implant surface: a preclinical study in foxhound dogs
Background: bioactive chemical surface modifications improve the wettability and osse-ointegration properties of titanium implants in both animals and humans. The objective of this animal study was to investigate and compare ... -
Human microbiota network: unveiling potential crosstalk between the different microbiota ecosystems and their role in health and disease
The human body is host to a large number of microorganisms which conform the human microbiota, that is known to play an important role in health and disease. Although most of the microorganisms that coexist with us are ... -
Influence of storage temperature and packaging on bacteria and yeast viability in a plant-based fermented food
Optimization of food storage has become a central issue for food science and biotechnology, especially in the field of functional foods. The aim of this work was to investigate the influence of different storage strategies ... -
Lactiplantibacillus plantarum DSM20174 attenuates the progression of non-alcoholic fatty liver disease by modulating gut microbiota, improving metabolic risk factors, and attenuating adipose inflammation
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, reaching epidemic proportions worldwide. Targeting the gut–adipose tissue–liver axis by modulating the gut microbiota can be a ... -
New insights into immunotherapy strategies for treating autoimmune diabetes
Type 1 diabetes mellitus (T1D) is an autoimmune illness that affects millions of patients worldwide. The main characteristic of this disease is the destruction of pancreatic insulin-producing beta cells that occurs due to ... -
Pediococcus acidilactici pA1c® improves the beneficial effects of metformin treatment in type 2 diabetes by controlling glycaemia and modulating intestinal microbiota
Type 2 diabetes (T2D) is a complex metabolic disease, which involves maintained hyperglycemia, mainly due to the development of an insulin resistance process. Metformin administration is the most prescribed treatment for ... -
Role of postbiotics in diabetes mellitus: current knowledge and future perspectives
In the last decade, the gastrointestinal microbiota has been recognised as being essential for health. Indeed, several publications have documented the suitability of probiotics, prebiotics, and symbiotics in the management ... -
Study of the stability of a plant-based fermented product and its effect in a murine model of type II diabetes
Esta tesis se basa en tres publicaciones científicas. En primer lugar, analizamos el efecto de la suplementación con Probisan® en la rata Zucker Diabetic Fatty, un modelo animal experimental de diabetes tipo 2, en un estudio ...