• Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus 

      Ruiz de los Mozos Aliaga, Igor Upna; Vergara Irigaray, Marta Upna; Segura, Víctor; Villanueva San Martín, Maite Upna Orcid; Bitarte, Nerea Upna; Saramago, Margarida; Domingues, Susana; Arraiano, Cecilia M.; Fechter, Pierre; Romby, Pascale; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
      The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ...
    • Genetic reductionist approach for studing the two-component signaling system in Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid (2014)   Tesis doctoral / Doktoretza tesia  OpenAccess
      Staphylococcus aureus es una bacteria ubicua capaz de colonizar una gran variedad de ambientes. En el hombre, S. aureus coloniza las fosas nasales, piel de las axilas, ingles, garganta o incluso el tracto intestinal. Se ...
    • Genome-wide antisense transcription drives mRNA processing in bacteria 

      Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid; Dobin, Alexander; Villanueva San Martín, Maite Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Vergara Irigaray, Marta Upna; Segura, Víctor; Fagegaltier, Delphine; Penadés, José R.; Valle Turrillas, Jaione Upna Orcid; Solano Goñi, Cristina Upna Orcid; Gingeras, Thomas R. (National Academy of Sciences, 2011)   Artículo / Artikulua  OpenAccess
      RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...
    • Insecticidal activity of bacillus thuringiensis proteins against coleopteran pests 

      Domínguez Arrizabalaga, Mikel Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Escriche, Baltasar; Ancín Azpilicueta, Carmen Upna Orcid; Caballero Murillo, Primitivo Upna Orcid (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Bacillus thuringiensis is the most successful microbial insecticide agent and its proteins have been studied for many years due to its toxicity against insects mainly belonging to the orders Lepidoptera, Diptera and ...
    • Novel application of bioassays and functional importance of minor crystal components of Bacillus thuringiensis serovar israelensis for dipteran pests 

      Valtierra de Luis, Daniel Upna Orcid (2020)   Tesis doctoral / Doktoretza tesia  OpenAccess
      Bacillus thuringiensis (Berliner, 1915) (Bt) es una bacteria Gram-positiva de forma redondeada que tiene la capacidad de formar esporas de resistencia. Bajo condiciones desfavorables, la bacteria esporula produciendo la ...
    • Novel Bacillus thuringiensis cry genes and their insecticidal potency against Coleoptera 

      Domínguez Arrizabalaga, Mikel Upna Orcid (2020)   Tesis doctoral / Doktoretza tesia
      Bacillus thuringiensis (Bt) se distingue de otras bacterias del género Bacillus por su capacidad de sintetizar d-endotoxinas (Cry y Cyt) que característicamente se agregan formando uno o más cristales paraesporales. Todas ...
    • Overlapping transcription and bacterial RNA removal 

      Lasa Uzcudun, Íñigo Upna Orcid; Villanueva San Martín, Maite Upna Orcid (National Academy of Sciences, 2014)   Artículo / Artikulua  OpenAccess
      The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...
    • Potential of Cry10Aa and Cyt2Ba, two minority δ-endotoxins produced by Bacillus thuringiensis ser. israelensis, for the control of Aedes aegypti larvae 

      Valtierra de Luis, Daniel Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Lai, Liliana Upna Orcid; Williams, Trevor Upna; Caballero Murillo, Primitivo Upna Orcid (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Bacillus thuringiensis ser. israelensis (Bti) has been widely used as microbial larvicide for the control of many species of mosquitoes and blackflies. The larvicidal activity of Bti resides in Cry and Cyt δ-endotoxins ...
    • Quantification of dose-mortality responses in adult Diptera: validation using Ceratitis capitata and Drosophila suzukii responses to spinosad 

      Valtierra de Luis, Daniel Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Caballero Sánchez, Javier Upna; Matas Casado, Isabel María Upna; Williams, Trevor Upna; Caballero Murillo, Primitivo Upna Orcid (Public Library of Science, 2019)   Artículo / Artikulua  OpenAccess
      Quantitative laboratory bioassay methods are required to evaluate the toxicity of novel insecticidal compounds for pest control and to determine the presence of resistance traits. We used a radioactive tracer based on ...
    • Regulation of heterogenous lexA expression in staphylococcus aureus by an antisense RNA originating from transcriptional read-through upon natural mispairings in the sbrB intrinsic terminator 

      Bastet, Laurène; Bustos-Sanmamed, Pilar; Catalán Moreno, Arancha; Caballero Sánchez, Carlos Upna; Cuesta Ferre, Sergio; Matilla Cuenca, Leticia Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Lasa Uzcudun, Íñigo; Toledo Arana, Alejandro (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Bacterial genomes are pervasively transcribed, generating a wide variety of antisense RNAs (asRNAs). Many of them originate from transcriptional read-through events (TREs) during the transcription termination process. ...
    • The regulon of the RNA chaperone CspA and its auto-regulation in Staphylococcus aureus 

      Caballero Sánchez, Carlos Upna; Menéndez Gil, Pilar; Catalán Moreno, Arancha; Vergara Irigaray, Marta Upna; García Martínez, Begoña Upna Orcid; Segura, Víctor; Irurzun Domínguez, Naiara; Villanueva San Martín, Maite Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Toledo Arana, Alejandro Upna Orcid (Oxford University Press, 2018)   Artículo / Artikulua  OpenAccess
      RNA-binding proteins (RBPs) are essential to finetune gene expression. RBPs containing the coldshock domain are RNA chaperones that have been extensively studied. However, the RNA targets and specific functions for ...
    • The role of ArlRS and VraSR in regulating ceftaroline hypersusceptibility in methicillin-resistant Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid; Roch, Melanie; Lasa Uzcudun, Íñigo Upna Orcid; Renzoni, Adriana; Kelley, William L. (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Methicillin-resistant Staphylococcus aureus infections are a global health problem. New control strategies, including fifth-generation cephalosporins such as ceftaroline, have been developed, however rare sporadic resistance ...
    • Sensory deprivation in Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid; García Martínez, Begoña Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Rapún Araiz, Beatriz Upna Orcid; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna Orcid; Martí, Miguel; Penadés, José R.; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Springer Nature, 2018)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ...
    • A strain of Bacillus thuringiensis containing a novel cry7Aa2 gene that is toxic to Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae) 

      Domínguez Arrizabalaga, Mikel Upna Orcid; Villanueva San Martín, Maite Upna Orcid; Fernández González, Ana Beatriz Upna; Caballero Murillo, Primitivo Upna Orcid (MDPI, 2019)   Artículo / Artikulua  OpenAccess
      The genome of the Bacillus thuringiensis BM311.1 strain was sequenced and assembled in 359 contigs containing a total of 6,390,221 bp. The plasmidic ORF of a putative cry gene from this strain was identified as a potential ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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