Listar por autor UPNA "Crespo, Helena"
Mostrando ítems 1-9 de 9
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Characterization of ovine A3Z1 restriction properties against small ruminant lentiviruses (SRLVs)
Intrinsic factors of the innate immune system include the apolipoprotein B editing enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. APOBEC3 inhibits replication of different virus families by cytosine ... -
Diagnosing infection with small ruminant lentiviruses of genotypes A and B by combining synthetic peptides in ELISA
The major challenges in diagnosing small ruminant lentivirus (SRLV) infection include early detection and genotyping of strains of epidemiological interest. A longitudinal study was carried out in Rasa Aragonesa sheep ... -
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ... -
Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit
β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ... -
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ... -
Ovine TRIM5α can restrict visna/maedi virus
The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored. Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ... -
Post-entry blockade of small ruminant lentiviruses by wild ruminants
Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ... -
Small ruminant macrophage polarization may play a pivotal role on lentiviral infection
Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ... -
Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep
Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...