Listar por autor "Cartas-Cejudo, Paz"
Mostrando ítems 1-7 de 7
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Alteration in the cerebrospinal fluid lipidome in Parkinson’s disease: a post-mortem pilot study
Fernández Irigoyen, Joaquín ; Cartas-Cejudo, Paz; Iruarrizaga-Lejarreta, Marta; Santamaría, Enrique (MDPI, 2021) Artículo / ArtikuluaLipid metabolism is clearly associated to Parkinson’s disease (PD). Although lipid homeostasis has been widely studied in multiple animal and cellular models, as well as in blood derived from PD individuals, the cerebrospinal ... -
Docosahexaenoic acid ameliorates contextual fear memory deficits in the Tg2576 Alzheimer´s disease mouse model: cellular and molecular correlates
Badesso, Sara; Cartas-Cejudo, Paz; Espelosín, María; Santamaría, Enrique; Cuadrado-Tejedor, Mar; García-Osta, Ana (MDPI, 2023) Artículo / ArtikuluaDocosahexaenoic acid (DHA), the most abundant polyunsaturated fatty acid in the brain, is essential for successful aging. In fact, epidemiological studies have demonstrated that increased intake of DHA might lower the ... -
Improvement of cognitive function in wild-type and Alzheimer's disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells
Casares, Noelia; Alfaro Larraya, María ; Cuadrado-Tejedor, Mar; Lasarte-Cía, Aritz; Navarro Negredo, Flor; Vivas, Isabel; Espelosín, María; Cartas-Cejudo, Paz; Fernández Irigoyen, Joaquín ; Santamaría, Enrique; García-Osta, Ana; Lasarte, Juan José (Frontiers Media, 2023) Artículo / ArtikuluaA complex network of interactions exists between the olfactory, immune and central nervous systems. In this work we intend to investigate this connection through the use of an immunostimulatory odorant like menthol, analyzing ... -
Olfactory bulb proteomics reveals widespread proteostatic disturbances in mixed dementia and guides for potential serum biomarkers to discriminate alzheimer disease and mixed dementia phenotypes
Lachén Montes, Mercedes ; Íñigo-Marco, Ignacio; Cartas-Cejudo, Paz; Fernández Irigoyen, Joaquín ; Santamaría, Enrique (MDPI, 2021) Artículo / ArtikuluaThe most common form of mixed dementia (MixD) is constituted by abnormal protein deposits associated with Alzheimer's disease (AD) that coexist with vascular disease. Although olfactory dysfunction is considered a clinical ... -
Olfactory characterization and training in older adults: protocol study
Zambom Ferraresi, Fabíola ; Zambom Ferraresi, Fabrício ; Fernández Irigoyen, Joaquín ; Lachén Montes, Mercedes ; Cartas-Cejudo, Paz; Lasarte, Juan José; Casares, Noelia; Fernández, Secundino; Cedeño Veloz, Bernardo Abel; Maraví-Aznar, Enrique; Uzcanga-Lacabe, María Itziar; Galbete Jiménez, Arkaitz ; Santamaría, Enrique; Martínez Velilla, Nicolás (Frontiers Media, 2021) Artículo / ArtikuluaThe aim of this article is to present the research protocol for a prospective cohort study that will assess the olfactory function and the effect of an intervention based on olfactory training in healthy very old adults ... -
Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory-entorhinal-amygdaloid axis in Alzheimer's and Parkinson's diseases
Cartas-Cejudo, Paz; Lachén Montes, Mercedes ; Ferrer, Isidro; Fernández Irigoyen, Joaquín; Santamaría, Enrique (BMC, 2023) Artículo / ArtikuluaBackground Smell impairment is one of the earliest features in Alzheimer’s (AD) and Parkinson’s diseases (PD). Due to sex diferences exist in terms of smell and olfactory structures as well as in the prevalence and ... -
Tackling the biological meaning of the human olfactory bulb dyshomeostatic proteome across neurological disorders: an integrative bioinformatic approach
Cartas-Cejudo, Paz; Lachén Montes, Mercedes ; Fernández Irigoyen, Joaquín ; Santamaría, Enrique (MDPI, 2021) Artículo / ArtikuluaOlfactory dysfunction is considered an early prodromal marker of many neurodegenerative diseases. Neuropathological changes and aberrant protein aggregates occur in the olfactory bulb (OB), triggering a tangled cascade of ...