Listar por autor "Segura, Víctor"
Mostrando ítems 1-7 de 7
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Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus
Ruiz de los Mozos Aliaga, Igor
; Vergara Irigaray, Marta ; Segura, Víctor; Villanueva San Martín, Maite 
; Bitarte, Nerea ; Saramago, Margarida; Domingues, Susana; Arraiano, Cecilia M.; Fechter, Pierre; Romby, Pascale; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro (Public Library of Science, 2013)
Artículo / Artikulua 
The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ... -
Genome expression profiling-based identification and administration efficacy of host-directed antimicrobial drugs against respiratory infection by nontypeable Haemophilus influenzae
Euba, Begoña; Moleres Apilluelo, Javier ; Segura, Víctor; Viadas Martínez, Cristina ; Morey Sancho, Pau; Moranta, David; Leiva, José; Torres, Juan de; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2015)
Artículo / Artikulua
Therapies that are safe, effective, and not vulnerable to developing resistance are highly desirable to counteract bacterial infections. Host-directed therapeutics is an antimicrobial approach alternative to conventional ... -
Genome-wide antisense transcription drives mRNA processing in bacteria
Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro ; Dobin, Alexander; Villanueva San Martín, Maite ; Ruiz de los Mozos Aliaga, Igor ; Vergara Irigaray, Marta ; Segura, Víctor; Fagegaltier, Delphine; Penadés, José R.; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Gingeras, Thomas R. (National Academy of Sciences, 2011)
Artículo / Artikulua
RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ... -
Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies
Lachén Montes, Mercedes ; Zelaya Huerta, María Victoria ; Segura, Víctor; Fernández Irigoyen, Joaquín ; Santamaría, Enrique (Impact Journals, 2017)
Artículo / Artikulua
Alzheimer´s disease (AD) is characterized by progressive dementia, initially presenting olfactory dysfunction. Despite the olfactory bulb (OB) is the first central structure of the olfactory pathway, we lack a complete ... -
The regulon of the RNA chaperone CspA and its auto-regulation in Staphylococcus aureus
Caballero Sánchez, Carlos; Menéndez Gil, Pilar; Catalán Moreno, Arancha; Vergara Irigaray, Marta ; García Martínez, Begoña ; Segura, Víctor; Irurzun Domínguez, Naiara; Villanueva San Martín, Maite ; Ruiz de los Mozos Aliaga, Igor ; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro (Oxford University Press, 2018)
Artículo / Artikulua
RNA-binding proteins (RBPs) are essential to finetune gene expression. RBPs containing the coldshock domain are RNA chaperones that have been extensively studied. However, the RNA targets and specific functions for ... -
Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray
Segura, Víctor; Toledo Arana, Alejandro ; Uzqueda, Maite; Lasa Uzcudun, Íñigo ; Muñoz Barrutia, Arrate (BioMed Central, 2012)
Artículo / Artikulua
Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ... -
Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma
Patiño García, Ana; Guruceaga, Elizabeth; Segura, Víctor; Sánchez Bayona, Rodrigo; Andueza, María Pilar; Tamayo Uria, Ibon; Serrano, Guillermo; Fusco, Juan Pablo; Pajares Villandiego, María Josefa ; Gúrpide, Alfonso; Ocón, Marimar; Sanmamed, Miguel F.; Rodríguez Ruiz, María; Melero, Ignacio; Lozano, María Dolores; Andrea, Carlos de; Pita, Guillermo; González Neira, Anna; González, Alvaro; Zulueta, Javier J.; Montuenga, Luis M.; Pío, Rubén; Pérez Gracia, José Luis (AME Publishing, 2021)
Artículo / Artikulua
Background: tobacco is the main risk factor for developing lung cancer. Yet, some heavy smokers do not develop lung cancer at advanced ages while others develop it at young ages. Here, we assess for the first time the ...
