Now showing items 1-3 of 3

    • Novel N,N′-disubstituted acylselenoureas as potential antioxidant and cytotoxic agents 

      Ruberte, Ana Carolina; Ramos Inza, Sandra; Aydillo, Carlos; Talavera, Irene; Encío Martínez, Ignacio Upna; Plano, Daniel; Sanmartín, Carmen (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Selenium compounds are pivotal in medicinal chemistry for their antitumoral and antioxidant properties. Forty seven acylselenoureas have been designed and synthesized following a fragment-based approach. Different scaffolds, ...
    • Novel selenadiazole derivatives as selective antitumor and radical scavenging agents 

      Ruberte, Ana Carolina; Plano, Daniel; Encío Martínez, Ignacio Upna; Aydillo, Carlos; Sharma, Arun K.; Sanmartín, Carmen (Elsevier, 2018)   Artículo / Artikulua  OpenAccess
      Twenty-seven novel benzo[c][1,2,5]selenadiazole-5-carboxylic acid (BSCA) derivatives were designed and synthesized. Anti-proliferative activity of these structures was tested in vitro against a panel of five human cancer ...
    • Synthesis and Leishmanicidal activity of novel urea, thiourea, and selenourea derivatives of diselenides 

      Díaz, Marta; Lucio, Hector de; Moreno, Esther; Espuelas, Socorro; Aydillo, Carlos; Jiménez Ruiz, Antonio; Toro, Miguel Ángel; Gutiérrez, Killian Jesús; Martínez Merino, Víctor Upna; Cornejo Ibergallartu, Alfonso Upna (American Society for Microbiology, 2019)   Artículo / Artikulua  OpenAccess
      A novel series of thirty-one N-substituted urea, thiourea, and selenourea derivatives containing diphenyldiselenide entities were synthesized, fully characterized by spectroscopic and analytical methods, and screened for ...