Browsing by Author "Campoy Sánchez, Susana"
Now showing items 1-6 of 6
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Beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus
Maiques, Elisa; Ubeda, Carles; Campoy Sánchez, Susana; Salvador, Noelia; Lasa Uzcudun, Íñigo; Novick, Richard P.; Barbé, Jordi; Penadés, José R. (American Society for Microbiology, 2006) Artículo / Artikulua
Antibiotics that interfere with DNA replication and cell viability activate the SOS response. In Staphylococcus aureus, the antibiotic-induced SOS response promotes replication and high-frequency horizontal transfer ... -
Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands
Tormo Más, María Ángeles; Mir, Ignacio; Shrestha, Archana; Tallent, Sandra M.; Campoy Sánchez, Susana; Lasa Uzcudun, Íñigo; Barbé, Jordi; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Nature Research, 2010) Artículo / Artikulua
Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ... -
Overexpression of the recA gene decreases oral but not intraperitoneal fitness of Salmonella enterica
Medina-Ruiz, Laura; Campoy Sánchez, Susana; Latasa Osta, Cristina; Cardenas, Paula; Alonso, Juan Carlos; Barbé, Jordi (American Society for Microbiology, 2010) Artículo / Artikulua
Transcription of the Salmonella enterica recA gene is negatively controlled by the LexA protein, the repressor of the SOS response. The introduction of a mutation (recAo6869) in the LexA binding site, in the promoter region ... -
RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
Ferrer, María Desamparados; Quiles Puchalt, Nuria; Harwich, Michael D.; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Barbé, Jordi; Lasa Uzcudun, Íñigo; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2011) Artículo / Artikulua
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ... -
Salmonella biofilm development depends on the phosphorylation status of RcsB
Latasa Osta, Cristina; García Martínez, Begoña
; Echeverz Sarasúa, Maite
; Toledo Arana, Alejandro
; Valle Turrillas, Jaione
; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina
; Lasa Uzcudun, Íñigo
(American Society for Microbiology, 2012) Artículo / Artikulua
The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ... -
A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria
Quiles Puchalt, Nuria; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Toledo Arana, Alejandro; Monedero, Vicente; Lasa Uzcudun, Íñigo
; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2013) Artículo / Artikulua
The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...