Listar por tema "Glioma"
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Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy
Adenovirus Delta-24-RGD has shown a remarkable efficacy in a phase I clinical trial for glioblastoma. Delta-24-RGD induces autophagy in glioma cells, however, the molecular derangements associated with Delta-24-RGD infection ... -
Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to increase the antiglioma ...