Now showing items 1-8 of 8

    • Absence of nuclear p16 is a diagnostic and independent prognostic biomarker in squamous cell carcinoma of the cervix 

      Mendaza Lainez, Saioa Upna; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; Zudaire, Tamara; Guarch, Rosa; Guerrero Setas, David (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      The tumor-suppressor protein p16 is paradoxically overexpressed in cervical cancer (CC). Despite its potential as a biomarker, its clinical value and the reasons for its failure in tumor suppression remain unclear. Our ...
    • Approaching the epigenome of triple negative breast cancer to identify new biomarkers 

      Mendaza Lainez, Saioa Upna (2020)   Tesis doctoral / Doktoretza tesia  OpenAccess
      El cáncer de mama (CM) es la neoplasia más frecuente en todo el mundo y la primera causa de muerte por cáncer en mujeres. El cáncer de mama triple negativo (CMTN) representa el 10-20% de todos los CM diagnosticados y es ...
    • Búsqueda de nuevos biomarcadores epigenéticos en cáncer de mama triple negativo 

      Ulazia Garmendia, Ane (2016)   Trabajo Fin de Máster/Master Amaierako Lana  OpenAccess
      Introducción El estudio de las alteraciones epigenéticas contribuye a la caracterización del subtipo triple negativo (TN) de cáncer de mama (CM). Objetivos Identificar genes diferencialmente metilados entre CM TN y ...
    • CDH22 hypermethylation is an independent prognostic biomarker in breast cancer 

      Martín Sánchez, Esperanza; Mendaza Lainez, Saioa Upna; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017)   Artículo / Artikulua  OpenAccess
      Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...
    • A DNA methylation-based gene signature can predict triple-negative breast cancer diagnosis 

      Mendaza Lainez, Saioa Upna; Guerrero Setas, David; Monreal Santesteban, Iñaki; Ulazia Garmendia, Ane; Córdoba Iturriagagoitia, Alicia; Cruz, Susana de la; Martín Sánchez, Esperanza (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Triple-negative breast cancer (TNBC) is the most aggressive breast cancer (BC) subtype and lacks targeted treatment. It is diagnosed by the absence of immunohistochemical expression of several biomarkers, but this method ...
    • Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures 

      Arechederra, María; Rullán, María Upna Orcid; Amat Villegas, Irene Upna; Oyón, Daniel; Zabalza, Lucía; Elizalde, María; Latasa, Maria Ujue; Mercado Gutiérrez, María R.; Ruiz-Clavijo, Daniel; Saldaña, Cristina; Fernández-Urién Sainz, Ignacio; Carrascosa, Juan; Jusué, Vanesa; Guerrero Setas, David; Zazpe, Cruz; González Borja, Iranzu; Sangro, Bruno; Herranz, José M.; Purroy, Ana; Gil, Isabel; Nelson, Leonard J.; Vila, Juan J.; Krawczyk, Marcin; Zieniewicz, Krzysztof; Patkowski, Waldemar; Milkiewicz, Piotr; Cubero, Francisco Javier; Alkorta Aranburu, Gorka; Fernández-Barrena, Maite G.; Urman, Jesús M.; Berasain, Carmen; Ávila, Matías A. (BMJ Publishing Group, 2021)   Artículo / Artikulua  OpenAccess
      Objective: despite significant progresses in imaging and pathological evaluation, early differentiation between benign and malignant biliary strictures remains challenging. Endoscopic retrograde cholangiopancreatography ...
    • A novel prognostic biomarker panel for early‐stage colon carcinoma 

      Azcue Sanromán, Pablo; Guerrero Setas, David; Encío Martínez, Ignacio Upna Orcid; Ibáñez Beroiz, B. Upna Orcid; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Molecular characterization of colorectal cancer has helped us understand better the biology of the disease. However, previous efforts have yet to provide significant clinical value in order to be integrated into clinical ...
    • PD-L1 as a prognostic factor in early-stage colon carcinoma within the immunohistochemical molecular subtype classification 

      Azcue Sanromán, Pablo; Encío Martínez, Ignacio Upna Orcid; Guerrero Setas, David; Suarez Alecha, Javier; Galbete Jiménez, Arkaitz Upna Orcid; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Colorectal cancer (CRC) is a very heterogeneous disease. Efforts to characterize and search for biomarkers for these patients are currently ongoing in the hope of establishing a more targeted therapeutic approach. The role ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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