Listar por tema "Interferon"
Mostrando ítems 1-2 de 2
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Cost efectiveness analysis of therapeutic strategies for patients with chronic hepatitis C previously non responders to interferon
Background: The efficacy of combination therapy in previous non responders to interferon (IFN) monotherapy with chronic hepatitis C is lower than in naïve patients, and there has been no economic evaluation in this population. ... -
PDL1 signals through conserved sequence motifs to overcome interferon-mediated cytotoxicity
PDL1 blockade produces remarkable clinical responses, thought to occur by T cell reactivation through prevention of PDL1-PD1 T cell inhibitory interactions. Here, we find that PDL1 cell-intrinsic signaling protects cancer ...