Now showing items 1-6 of 6

    • Characterization of nontypable haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection 

      Garmendia, Junkal; Viadas Martínez, Cristina Upna; Calatayud, Laura; Mell, Joshua Chang; Martí Lliteras, Pau; Euba, Begoña; Llobet, Enrique; Gil Puig, Carmen Upna; Bengoechea Alonso, José Antonio; Redfield, Rosemary J.; Liñares, Josefina (Public Library of Science, 2014)   Artículo / Artikulua  OpenAccess
      Nontypable Haemophilus influenzae (NTHi) has emerged as an important opportunistic pathogen causing infection in adults suffering obstructive lung diseases. Existing evidence associates chronic infection by NTHi to the ...
    • Deciphering tissue-induced Klebsiella pneumoniae lipid A structure 

      Llobet, Enrique; Martínez Moliner, Verónica; Moranta, David; Dahlström, Käthe M.; Regueiro, Verónica; Tomás, Anna; Cano, Victoria; Pérez Gutiérrez, Camino; Frank, Christian G.; Garmendia García, Juncal (National Academy of Sciences, 2015)   Artículo / Artikulua  OpenAccess
      The outcome of an infection depends on host recognition of the pathogen, hence leading to the activation of signaling pathways controlling defense responses. A long-held belief is that the modification of the lipid A ...
    • Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells 

      March, Catalina; Moranta, David; Regueiro, Verónica; Llobet, Enrique; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Biochemistry and Molecular Biology, 2011)   Artículo / Artikulua  OpenAccess
      Outer membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated Gram-negative pathogen. It is an important cause ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero-Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella 

      Insua, José Luis; Llobet, Enrique; Moranta, David; Pérez Gutiérrez, Camino; Tomás, Anna; Garmendia García, Juncal; Bengoechea, José A. (American Society for Microbiology, 2013)   Artículo / Artikulua  OpenAccess
      The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ...
    • Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes 

      March, Catalina; Cano, Victoria; Moranta, David; Llobet, Enrique; Pérez Gutiérrez, Camino; Tomás, Juan M.; Suárez, Teresa; Garmendia, Junkal; Bengoechea Alonso, José Antonio (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
      Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...