Listar por autor "Mell, Joshua Chang"
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Antagonistic pleiotropy in the bifunctional surface protein fadl (OmpP1) during adaptation of Haemophilus influenzae to chronic lung infection associated with chronic obstructive pulmonary disease
Moleres Apilluelo, Javier ; Fernández Calvet, Ariadna ; Ehrlich, Rachel L.; Martí, Sara; Pérez Regidor, Lucía; Euba, Begoña; Rodríguez Arce, Irene ; Balashov, Sergey; Cuevas, Ester; Liñares, Josefina; Ardanuy, Carmen; Martín Santamaría, Sonsoles; Ehrlich, Garth D.; Mell, Joshua Chang; Garmendia García, Juncal (American Society for Microbiology, 2018) Artículo / ArtikuluaTracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects ... -
Characterization of nontypable haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection
Garmendia García, Juncal; Viadas Martínez, Cristina ; Calatayud, Laura; Mell, Joshua Chang; Martí Lliteras, Pau; Euba, Begoña; Llobet, Enrique; Gil Puig, Carmen ; Bengoechea Alonso, José Antonio; Redfield, Rosemary J.; Liñares, Josefina (Public Library of Science, 2014) Artículo / ArtikuluaNontypable Haemophilus influenzae (NTHi) has emerged as an important opportunistic pathogen causing infection in adults suffering obstructive lung diseases. Existing evidence associates chronic infection by NTHi to the ... -
Complete genome sequence of Haemophilus influenzae strain 375 from the middle ear of a pediatric patient with otitis media
Mell, Joshua Chang; Sinha, Sunita; Balashov, Sergey; Viadas Martínez, Cristina ; Garmendia García, Juncal (American Society for Microbiology, 2014) Artículo / ArtikuluaOriginally isolated from a pediatric patient with otitis media, Haemophilus influenzae strain 375 (Hi375) has been extensively studied as a model system for intracellular invasion of airway epithelial cells and other ... -
Transformed recombinant enrichment profiling rapidly identifies HMW1 as an intracellular invasion locus in Haemophilus influenzae
Mell, Joshua Chang; Viadas Martínez, Cristina ; Moleres Apilluelo, Javier ; Sinha, Sunita; Fernández Calvet, Ariadna ; Porsch, Eric A.; St. Geme, Joseph W.; Nislow, Corey; Redfield, Rosemary J.; Garmendia García, Juncal (Public Library of Science, 2016) Artículo / ArtikuluaMany bacterial species actively take up and recombine homologous DNA into their genomes, called natural competence, a trait that offers a means to identify the genetic basis of naturally occurring phenotypic variation. ...