Now showing items 1-5 of 5

    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios Chaves, Leyre; Conde Álvarez, Raquel; Gil Ramírez, Yolanda Upna; Zúñiga Ripa, Amaia; Barquero-Calvo, Elías; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; Miguel, María Jesús de; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; Iriarte, Maite (Public Library of Science, 2011)   Artículo / Artikulua  OpenAccess
      The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ...
    • Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export 

      González, David; Grilló Dolset, María Jesús; Miguel, María Jesús de; Ali, Tara; Arce Gorvel, Vilma; Delrue, Rose May; Conde Álvarez, Raquel; Muñoz Álvaro, Pilar María; López Goñi, Ignacio; Iriarte, Maite; Marín, Clara M.; Weintraub, Andrej; Widmalm, Goeran; Zygmunt, Michel; Letesson, Jean-Jacques; Gorvel, Jean-Pierre; Blasco, José María Upna; Moriyón Uría, Ignacio (Public Library of Science, 2008)   Artículo / Artikulua  OpenAccess
      Background: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ...
    • BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence 

      Manterola, Lorea; Guzman-Verri, Caterina; Chaves Olarte, Esteban; Barquero-Calvo, Elías; Miguel, María Jesús de; Moriyon, Ignacio; Grilló Dolset, María Jesús; López Goñi, Ignacio; Moreno, Edgardo (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ...
    • Role of the Omp25/Omp31 family in outer membrane properties and virulence of Brucella ovis 

      Caro-Hernandez, Paola; Fernandez-Lago, Luis; Miguel, María Jesús de; Martin-Martin, Ana I.; Cloeckaert, Axel; Grilló Dolset, María Jesús; Vizcaíno, Nieves (American Society for Microbiology, 2007)   Artículo / Artikulua  OpenAccess
      The genes coding for the five outer membrane proteins (OMPs) of the Omp25/Omp31 family expected to be located in the outer membrane (OM) of rough virulent Brucella ovis PA were inactivated to evaluate their role in virulence ...
    • Spatial distribution and risk factors of brucellosis in Iberian wild ungulates 

      Muñoz Álvaro, Pilar María; Boadella, Mariana; Arnal, Maricruz; Miguel, María Jesús de; Revilla, Miguel; Martínez, David; Vicente, Joaquín; Acevedo, Pelayo; Oleaga, Álvaro; Ruiz Fons, Francisco; Marín, Clara M.; Prieto, José M.; Fuente, José de la; Barral, Marta; Barberán, Montserrat; Fernández de Luco, Daniel; Blasco, José María Upna; Gortázar, Christian (BioMed Central, 2010)   Artículo / Artikulua  OpenAccess
      Background: The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribution ...