Now showing items 1-5 of 5

    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios Chaves, Leyre; Conde Álvarez, Raquel; Gil Ramírez, Yolanda Upna; Zúñiga Ripa, Amaia; Barquero-Calvo, Elías; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; Miguel, María Jesús de; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; Iriarte, Maite (Public Library of Science, 2011)   Artículo / Artikulua  OpenAccess
      The brucellae are alpha-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked ...
    • Brucellosis vaccines: assessment of brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export 

      González, David; Grilló Dolset, María Jesús; Miguel, María Jesús de; Ali, Tara; Arce Gorvel, Vilma; Delrue, Rose May; Conde Álvarez, Raquel; Muñoz Álvaro, Pilar María; López Goñi, Ignacio; Iriarte, Maite; Marín, Clara M.; Weintraub, Andrej; Widmalm, Goeran; Zygmunt, Michel; Letesson, Jean-Jacques; Gorvel, Jean-Pierre; Blasco, José María Upna; Moriyón Uría, Ignacio (Public Library of Science, 2008)   Artículo / Artikulua  OpenAccess
      Background: The brucellae are facultative intracellular bacteria that cause brucellosis, one of the major neglected zoonoses. In endemic areas, vaccination is the only effective way to control this disease. Brucella ...
    • The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice 

      San Román Aberasturi, Beatriz Upna; Lasa Uzcudun, Íñigo Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria Upna; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña Upna; Andrés, Ximena de; Zabaleta, Virginia Upna; Mansilla, Cristina; Farrán Blanch, Inmaculada Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
    • Genetic analysis of Coprinopsis cinerea mutants with defects in fruiting body development 

      Srivilai, Prayook; Chaiseana, Wassana; Kües, Ursula (Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa, 2006)   Contribución a congreso / Biltzarrerako ekarpena  OpenAccess
      Few genes have so far been cloned and characterized in fruiting of the heterothallic mushroom Coprinopsis cinerea. Fruiting body development normally occurs on the dikaryon. However, the binucleate state of the mycelium ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero-Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...