Browsing by Author "Nistal, Manuel"

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Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma

Lázcoz, Paula ; Muñoz, Jorge; Nistal, Manuel; Pestaña, Ángel; Encío Martínez, Ignacio ; Sáez Castresana, Javier (BioMed Central, 2006) Artículo / Artikulua

Background: Epigenetic alterations and loss of heterozygosity are mechanisms of tumor suppressor gene inactivation. A new carcinogenic pathway, targeting the RAS effectors has recently been documented. RASSF1A, on 3p21.3, ...