Listar por autor "Pío, Rubén"
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Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma
Valencia, Karmele; Sainz, Cristina; Bertolo, Cristina; Biurrun, Gabriel de; Agorreta Arrazubi, Jackeline; Azpilikueta, Arantza; Larrayoz, Marta; Bosco, Graziella; Zandueta, Carolina; Redrado, Miriam; Redin, Esther; Expósito, Francisco; Serrano, Diego; Echepare, Mirari; Ajona, Daniel; Melero, Ignacio; Pío, Rubén; Thomas, Roman; Calvo, Alfonso; Montuenga, Luis M. (The Company of Biologists, 2022) Artículo / ArtikuluaThere is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, ... -
Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma
Patiño García, Ana; Guruceaga, Elizabeth; Segura, Víctor; Sánchez Bayona, Rodrigo; Andueza, María Pilar; Tamayo Uria, Ibon; Serrano, Guillermo; Fusco, Juan Pablo; Pajares Villandiego, María Josefa ; Gúrpide, Alfonso; Ocón, Marimar; Sanmamed, Miguel F.; Rodríguez Ruiz, María; Melero, Ignacio; Lozano, María Dolores; Andrea, Carlos de; Pita, Guillermo; González Neira, Anna; González, Alvaro; Zulueta, Javier J.; Montuenga, Luis M.; Pío, Rubén; Pérez Gracia, José Luis (AME Publishing, 2021) Artículo / ArtikuluaBackground: tobacco is the main risk factor for developing lung cancer. Yet, some heavy smokers do not develop lung cancer at advanced ages while others develop it at young ages. Here, we assess for the first time the ...