Listar por autor "Pineda Lucena, Antonio"
Mostrando ítems 1-2 de 2
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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer
Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; López Erdozain, Inés; Rodríguez-Remírez, María; Palomino Echeverría, Sara ; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz Sarvisé, Mariano; Pineda Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaría, Enrique; Fernández Irigoyen, Joaquín ; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silvestre (Springer Nature, 2023) Artículo / ArtikuluaDrug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the ... -
Splicing factor SLU7 prevents oxidative stress-mediated hepatocyte nuclear factor 4α degradation, preserving hepatic differentiation and protecting from liver damage
Gárate Rascón, María; Recalde, Miriam; Jiménez, Maddalen; Elizalde, María; Azkona, María; Uriarte, Iker; Latasa, Maria Ujue; Urtasun Alonso, Raquel ; Bilbao, Idoia; Sangro, Bruno; García Ruiz, Carmen; Fernández-Checa, José Carlos; Corrales, Fernando J.; Esquivel, Argitxu; Pineda Lucena, Antonio; Fernández-Barrena, Maite G.; Ávila, Matías A.; Arechederra, María; Berasain, Carmen (WileyAmerican Asociation for the Study of Liver Diseases, 2021) Artículo / ArtikuluaBackground and Aims: Hepatocellular dedifferentiation is emerging as an important determinant in liver disease progression. Preservation of mature hepatocyte identity relies on a set of key genes, predominantly the ...