• Functional improvement of human cardiotrophin 1 produced in tobacco chloroplasts by co-expression with plastid thioredoxin m 

      Ancín Rípodas, María Upna Orcid; Sanz Barrio, Ruth Upna; Santamaría, Eva; Fernández San Millán, Alicia Upna Orcid; Larraya Reta, Luis María Upna Orcid; Veramendi Charola, Jon Upna Orcid; Farrán Blanch, Inmaculada Upna Orcid (MDPI, 2020)   Artículo / Artikulua  OpenAccess
      Human cardiotrophin 1 (CT1), a cytokine with excellent therapeutic potential, was previously expressed in tobacco chloroplasts. However, the growth conditions required to reach the highest expression levels resulted in an ...
    • Increased bioethanol production from commercial tobacco cultivars overexpressing thioredoxin f grown under field conditions 

      Farrán Blanch, Inmaculada Upna Orcid; Fernández San Millán, Alicia Upna Orcid; Ancín Rípodas, María Upna Orcid; Larraya Reta, Luis María Upna Orcid; Veramendi Charola, Jon Upna Orcid (Springer, 2014)   Artículo / Artikulua  OpenAccess
      Bioethanol is mainly produced from food crops such as sugar cane and maize while it has been held partly responsible for the rise of food commodity prices. Tobacco, integrated in biorefinery facilities for the extraction ...
    • New in vivo approach to broaden the thioredoxin family interactome in chloroplasts 

      Ancín Rípodas, María Upna Orcid; Fernández Irigoyen, Joaquín Upna Orcid; Santamaría, Enrique; Larraya Reta, Luis María Upna Orcid; Fernández San Millán, Alicia Upna Orcid; Veramendi Charola, Jon Upna Orcid; Farrán Blanch, Inmaculada (MDPI, 2022)   Artículo / Artikulua  OpenAccess
      Post-translational redox modifications provide an important mechanism for the control of major cellular processes. Thioredoxins (Trxs), which are key actors in this regulatory mechanism, are ubiquitous proteins that catalyse ...
    • NTRC and thioredoxin f overexpression differentially induces starch accumulation in tobacco leaves 

      Ancín Rípodas, María Upna Orcid; Larraya Reta, Luis María Upna Orcid; Fernández San Millán, Alicia Upna Orcid; Veramendi Charola, Jon Upna Orcid; Burch Smith, Tessa; Farrán Blanch, Inmaculada Upna Orcid (MDPI, 2019)   Artículo / Artikulua  OpenAccess
      Thioredoxin (Trx) f and NADPH-dependent Trx reductase C (NTRC) have both been proposed as major redox regulators of starch metabolism in chloroplasts. However, little is known regarding the specific role of each protein ...
    • Overexpression of plastidial thioredoxin f leads to enhanced starch accumulation in tobacco leaves 

      Sanz Barrio, Ruth Upna; Corral-Martínez, Patricia; Ancín Rípodas, María Upna Orcid; Seguí-Simarro, José M.; Farrán Blanch, Inmaculada Upna Orcid (Wiley, 2013)   Artículo / Artikulua  OpenAccess
      Starch, the most abundant storage carbohydrate in plants, has been a major feedstock for first‐generation biofuels. Growing fuel demands require, however, that the starch yields of energy crops be improved. Leaf starch is ...
    • Overexpression of plastidial thioredoxins f and m differentially alters photosynthetic activity and response to oxidative stress in tobacco plants 

      Rey, Pascal; Sanz Barrio, Ruth Upna; Innocenti, Gilles; Ksas, Brigitte; Courteille, Agathe; Rumeau, Dominique; Issakidis Bourguet, Emmanuelle; Farrán Blanch, Inmaculada Upna Orcid (Frontiers Media, 2013)   Artículo / Artikulua  OpenAccess
      Plants display a remarkable diversity of thioredoxins (Trxs), reductases controlling the thiol redox status of proteins. The physiological function of many of them remains elusive, particularly for plastidial Trxs f and ...
    • Overexpression of thioredoxin m in chloroplasts alters carbon and nitrogen partitioning in tobacco 

      Ancín Rípodas, María Upna Orcid; Larraya Reta, Luis María Upna Orcid; Florez-Sarasa, Igor; Bénard, Camille; Fernández San Millán, Alicia Upna Orcid; Veramendi Charola, Jon Upna Orcid; Gibon, Yves; Fernie, Alisdair R.; Aranjuelo Michelena, Iker Upna Orcid; Farrán Blanch, Inmaculada Upna Orcid (Oxford University Press, 2021)   Artículo / Artikulua  OpenAccess
      In plants, there is a complex interaction between carbon (C) and nitrogen (N) metabolism, and its coordination is fundamental for plant growth and development. Here, we studied the influence of thioredoxin (Trx) m on C and ...
    • Overexpression of thioredoxin m in tobacco chloroplasts inhibits the protein kinase STN7 and alters photosynthetic performance 

      Ancín Rípodas, María Upna Orcid; Fernández San Millán, Alicia Upna Orcid; Larraya Reta, Luis María Upna Orcid; Morales Iribas, Fermín; Veramendi Charola, Jon Upna Orcid; Aranjuelo Michelena, Iker Upna Orcid; Farrán Blanch, Inmaculada Upna Orcid (Oxford University Press, 2019)   Artículo / Artikulua  OpenAccess
      The activity of the protein kinase STN7, involved in phosphorylation of the light-harvesting complex II (LHCII) proteins, has been reported as being co-operatively regulated by the redox state of the plastoquinone pool ...
    • Post-harvest light treatment increases expression levels of recombinant proteins in transformed plastids of potato tubers 

      Larraya Reta, Luis María Upna Orcid; Fernández San Millán, Alicia Upna Orcid; Ancín Rípodas, María Upna Orcid; Farrán Blanch, Inmaculada Upna Orcid; Veramendi Charola, Jon Upna Orcid (Wiley, 2015)   Artículo / Artikulua  OpenAccess
      Plastid genetic engineering represents an attractive system for the production of foreign proteins in plants. Although high expression levels can be achieved in leaf chloroplasts, the results for non-photosynthetic plastids ...
    • Tobacco plastidial thioredoxins as modulators of recombinant protein production in transgenic chloroplasts 

      Sanz Barrio, Ruth Upna; Fernández San Millán, Alicia Upna Orcid; Corral-Martínez, Patricia; Seguí-Simarro, José M.; Farrán Blanch, Inmaculada Upna Orcid (Wiley, 2011)   Artículo / Artikulua  OpenAccess
      Thioredoxins (Trxs) are small ubiquitous disulphide proteins widely known to enhance expression and solubility of recombinant proteins in microbial expression systems. Given the common evolutionary heritage of chloroplasts ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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