Listar por tema "Two-component systems"
Mostrando ítems 1-6 de 6
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Papel de los sistemas de dos componentes de Staphylococcus aureus en la susceptibilidad a complestatina y corbomicina y en la regulación génica en ausencia de fosforilación
(2022) Tesis doctoral / Doktoretza tesiaStaphylococcus aureus es una bacteria versátil que se puede encontrar estableciendo una relación comensal en la piel de, aproximadamente, el 30% de la población sin causar ningún problema. Sin embargo, cuando ésta atraviesa ... -
Regulation of gene expression by non-phosphorylated response regulators
Two-component systems (TCSs) are a prominent sensory system in bacteria. A prototypical TCS comprises a membrane-bound sensor histidine kinase (HK) responsible for sensing the signal and a cytoplasmic response regulator ... -
The role of ArlRS and VraSR in regulating ceftaroline hypersusceptibility in methicillin-resistant Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus infections are a global health problem. New control strategies, including fifth-generation cephalosporins such as ceftaroline, have been developed, however rare sporadic resistance ... -
Sensory deprivation in Staphylococcus aureus
Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ... -
A systematic evaluation of the two-component systems network reveals that ArlRS is a key regulator of catheter colonization by Staphylococcus aureus
Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the ... -
Systematic reconstruction of the complete two-component sensorial network in staphylococcus aureus
In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different ...