• Investigar es mirar lo que todos ven pero pensándolo de una manera diferente 

  López-Goñi, José Javier  (Asociación Proyecto Hombre, 2018)   Artículo / Artikulua  

  En este artículo se presentan los principales resultados de una línea de investigación que comenzó hace varios años el grupo de investigación en Psicología Clínica y Psicopatología de la Universidad Pública de Navarra en ...

• Alcohol consumption in university professors: the role of stress and gender 

  Ruisoto, Pablo; Vaca, Silvia L.; López Goñi, José Javier ; Cacho Fernández, Raúl ; Fernández Suárez, Iván (2018)   Capítulo de libro / Liburuen kapitulua  

  The role of job satisfaction and other psychosocial variables in problematic alcohol consumption within professional settings remains understudied. The aim of this study is to assess the level ...

• Morphological and biochemical characterization of a cell death process induced by E3, a new synthetic diarylsulfonilurea analogue 

  Alonso Roldán, Marta; Miglaccio, M.; Encío Martínez, Ignacio ; Asumendi, A.; Martínez Merino, Víctor; Hilario, E.; García, M. (Hindawi, 2001)   Otro / Bestelakoa  

  With a view to finding new compounds with improved antitumoral activity and reduced secondary effects, our group, using theoretical structure-activity studies, has designed several analogues and derivatives of ...

• Promoter methylation of RASSF1A associates to adult secondary glioblastomas and pediatric glioblastomas 

  Muñoz, Jorge; Inda, María del Mar; Lázcoz, Paula ; Zazpe, Idoya; Fan, Xing; Alfaro, Jorge; Tuñón Álvarez, Teresa; Rey, Juan A.; Castresana, Javier S. (Hindawi / Wiley, 2012)   Artículo / Artikulua  

  While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is still a matter of study. We analyzed the frequency of promoter ...

• Trends in hospital morbidity from Alzheimer's disease in the European Union, 2000-2014 

  Niu, Hao; Álvarez Álvarez, Ismael; Aguinaga Ontoso, Inés ; Guillén Grima, Francisco  (SAGE, 2018)   Artículo / Artikulua  

  Background: Alzheimer’s disease (AD) has become a concerning public health issue. We aimed to analyse the trends of hospital morbidity from AD in the European Union (EU) in the period 2000-2014. Methods: Data from ...

• CDH22 hypermethylation is an independent prognostic biomarker in breast cancer 

  Martín, Esperanza; Mendaza Lainez, Saioa; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero, David (BioMed Central, 2017)   Artículo / Artikulua  

  Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...

• Network-driven proteogenomics unveils an aging-related imbalance in the olfactory IκBα-NFκB p65 complex functionality in Tg2576 Alzheimer’s disease mouse model 

  Palomino Alonso, Maialen; Lachén Montes, Mercedes; González Morales, Andrea; Ausín, Karina; Pérez Mediavilla, Alberto; Fernández Irigoyen, Joaquín; Santamaría, Enrique (MDPI, 2017)   Artículo / Artikulua  

  Olfaction is often deregulated in Alzheimer’s disease (AD) patients, and is also impaired in transgenic Tg2576 AD mice, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little ...

• High intensity interval- vs resistance or combined-training for improving cardiometabolic health in overweight adults (cardiometabolic HIIT-RT study): study protocol for a randomised controlled trial 

  Ramírez Vélez, Robinson; Hernández, Alejandra; Castro, Karem; Tordecilla Sanders, Alejandra; González Ruiz, Katherine; Correa Bautista, Jorge Enrique; Izquierdo Redín, Mikel ; García Hermoso, Antonio (BioMed Central, 2016)   Artículo / Artikulua  

  Background: Although evidence shows the positive health effects of physical activity, most of the adult population in Colombia are sedentary. It is, therefore, important to implement strategies that generate changes in ...

• Prevention of diabetes in overweight/obese children through a family based intervention program including supervised exercise (PREDIKID project): study protocol for a randomized controlled trial 

  Arenaza, Lide; Medrano, María; Amasene, María; Rodríguez Vigil, Beatriz; Díez, Ignacio; Graña, Manuel; Tobalina, Ignacio; Maiz, Edurne; Arteche, Edurne; Larrarte, Eider; Huybrechts, Inge; Davis, Catherine L.; Ruiz, Jonatan R.; Ortega, Francisco B.; Margareto, Javier; Labayen Goñi, Idoia (BioMed Central, 2017)   Artículo / Artikulua  

  Background: The global pandemic of obesity has led to an increased risk for prediabetes and type-2 diabetes (T2D). The aims of the current project are: (1) to evaluate the effect of a 22-week family based intervention program, ...

• Diferencias entre los intentos de suicidio y otras urgencias psiquiátricas hospitalarias 

  Goñi-Sarriés, Adriana; Janda-Galán, Lucía; Macaya-Aranguren, Patricia; Azcárate, Leire; López-Goñi, José Javier ; Álvarez, Ignacio (Fundación López Ibor, 2018)   Artículo / Artikulua  

  Introducción. No se han encontrado estudios en España que comparen el perfil de los pacientes atendidos en urgencias de psiquiatría por un intento de suicidio con los que acuden por otro motivo. El objetivo de este estudio ...

• Suicidal attempts among patients with substance use disorders who present with suicidal ideation 

  López-Goñi, José Javier ; Fernández-Montalvo, Javier ; Arteaga Olleta, Alfonso ; Haro Escribano, Begoña (Elsevier, 2019)   Artículo / Artikulua

  Background and aims: Patients with addictions have a great risk of suicidal ideation and attempts. Suicidal behaviour is a continuum that begins with ideation and may continue with planning, ...

• Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression 

  Lachén Montes, Mercedes; González Morales, Andrea; Zelaya, María Victoria; Pérez Valderrama, Estela; Ausín, Karina; Ferrer, Isidro; Fernández Irigoyen, Joaquín; Santamaría, Enrique (Springer Nature, 2017)   Artículo / Artikulua  

  Olfactory dysfunction is among the earliest features of Alzheimer’s disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here, OB- ...

• Efecto de la nueva regulación antitabaco en Italia 

  Rodríguez Nieto, María Teresa; Gallus, Silvano; Chatenoud, Liliane; Zuccaro, Piergiorgio; Colombo, Paolo; Apolone, Giovanni; Pacifici, Roberta; Garattini, Silvio; La Vecchia, Carlo (Instituto Nacional de Salud Pública, 2006)   Artículo / Artikulua  

  Objetivo: se realizó un estudio poblacional para conocer las actitudes relacionadas con la Nueva Ley Italiana Antitabaco y el efecto sobre el consumo. Material y métodos: se analizó una muestra de 3 114 individuos mayores ...

• Perfil de la demanda urgente e influencia del fútbol televisado en un servicio extrahospitalario en la Zona Básica de Salud de Tafalla, Navarra 

  Pérez Ciordia, Ignacio ; Catalán Fabo, Francisca; Zalacain Nicolay, Fernando; Barriendo Antoñanzas, Maite; Solaegui Díaz de Guereñu, Ramón; Guillén Grima, Francisco  (Ministerio de Sanidad y Consumo, 2003)   Artículo / Artikulua  

  Fundamento: la demanda a los servicios de urgencias, tanto hospitalarios como extrahospitalarios, mantiene un ritmo creciente. El objetivo del presente trabajo es doble: cuantificación y estudio de las características ...

• Prevalencia de actividad física y su relación con variables sociodemográficas y estilos de vida en la población de 18 a 65 años de Pamplona 

  Elizondo Armendáriz, José Javier; Guillén Grima, Francisco ; Aguinaga Ontoso, Inés  (Ministerio de Sanidad, Servicios Sociales e Igualdad, 2005)   Artículo / Artikulua  

  Fundamento: los conocimientos actuales permiten considerar que existe una asociación de tipo causal entre el nivel de actividad física y la aparición de diversas enfermedades. A pesar de ello, la actividad física es una ...

• Suicidal ideation and attempts in patients who seek treatment for substance use disorder 

  López-Goñi, José Javier ; Fernández-Montalvo, Javier ; Arteaga Olleta, Alfonso ; Haro Escribano, Begoña (Elsevier, 2018)   Artículo / Artikulua  

  Patients with substance dependence have a great risk of suicidal ideation and attempts. The study of the specific risk characteristics of patients with substance use disorders who present with suicidal ideation and/or ...

• Reliability of health-related physical fitness tests among Colombian children and adolescents: the FUPRECOL study 

  Ramírez Vélez, Robinson; Rodrigues Bezerra, Diogo; Correa Bautista, Jorge Enrique; Izquierdo Redín, Mikel ; Lobelo, Felipe (Public Library of Science, 2015)   Artículo / Artikulua  

  Substantial evidence indicates that youth physical fitness levels are an important marker of lifestyle and cardio-metabolic health profiles and predict future risk of chronic diseases. The reliability physical fitness ...

• Quantitative measurements in the human hippocampus and related areas: correspondence between ex-vivo MRI and histological preparations 

  Delgado González, José Carlos; Mansilla Legorburo, Francisco; Florensa Vila, José; Insausti Serrano, Ana María; Viñuela, Antonio; Tuñón Álvarez, Teresa; Cruz, Marcos; Mohedano Moriano, Alicia; Insausti, Ricardo; Artacho Pérula, Emilio (Public Library of Science, 2015)   Artículo / Artikulua  

  The decrease of volume estimates in different structures of the medial temporal lobe related to memory correlate with the decline of cognitive functions in neurodegenerative diseases. This study presents data on the ...

• Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatment 

  Celay Leoz, Ion; Blanco Luquin, Idoia; Lázcoz, Paula ; Rotinen Díaz, Mirja Sofia; Castresana, Javier S.; Encío Martínez, Ignacio  (Public Library of Science, 2013)   Artículo / Artikulua  

  To determine the effect of retinoic acid (RA) in neuroblastoma we treated RA sensitive neuroblastoma cell lines with 9-cis RA or ATRA for 9 days, or for 5 days followed by absence of RA for another 4 days. Both isomers ...

• The chronic effects of low- and high-intensity resistance training on muscular fitness in adolescents 

  Assunção, Ari R.; Bottaro, Martim; Ferreira Junior, João B.; Izquierdo Redín, Mikel ; Lusa Cadore, Eduardo; Gentil, Paulo (Public Library of Science, 2016)   Artículo / Artikulua  

  To compare the effects of high-load, low-repetition maximum (LRM) and low-load, high-repetition maximum (HRM) resistance training regimens on muscular fitness in untrained adolescents. Forty-five untrained adolescents ...

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