Listar Artículos de revista DCS - OZS Aldizkari artikuluak por autor UPNA "Lasa Uzcudun, Íñigo"

Mostrando ítems 1-14 de 14

    • Antibiofilm activity of flavonoids on staphylococcal biofilms through targeting BAP amyloids 

      Matilla Cuenca, Leticia Upna Orcid; Gil Puig, Carmen Upna Orcid; Cuesta Ferre, Sergio; Rapún Araiz, Beatriz Upna Orcid; Mira, Alex; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid; Ziemité, Miglé (Nature Research, 2020)   Artículo / Artikulua  OpenAccess
      The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the ...

    • Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection 

      Svensson Malchau, Karin; Tillander, Jonatan; Zaborowska, Magdalena; Hoffman, Maria; Lasa Uzcudun, Íñigo Upna Orcid; Thomsen, Peter; Malchau, Henrik; Rolfson, Ola; Trobos, Margarita (Elsevier, 2021)   Artículo / Artikulua  OpenAccess
      Background: periprosthetic joint infections (PJI) are challenging complications following arthroplasty. Staphylococci are a frequent cause of PJI and known biofilm producers. Biofilm formation decreases antimicrobial ...

    • The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers 

      Taglialegna, Agustina Upna; Matilla Cuenca, Leticia Upna Orcid; Dorado Morales, Pedro Upna Orcid; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (Nature ResearchNanyang Technological University (Singapur), 2020)   Artículo / Artikulua  OpenAccess
      Functional amyloids are considered as common building block structures of the biofilm matrix in different bacteria. In previous work, we have shown that the staphylococcal surface protein Bap, a member of the Biofilm-Associated ...

    • A DIVA vaccine strain lacking RpoS and the secondary messenger c-di-GMP for protection against salmonellosis in pigs 

      Gil Puig, Carmen Upna Orcid; Latasa Osta, Cristina Upna; García Ona, Enrique Upna; Lázaro, Isidro; Labairu, Javier; Echeverz Sarasúa, Maite Upna Orcid; Burgui Erice, Saioa Upna Orcid; García Martínez, Begoña Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Solano Goñi, Cristina Upna Orcid (BioMed Central, 2020)   Artículo / Artikulua  OpenAccess
      Salmonellosis is the second most common food-borne zoonosis in the European Union, with pigs being a major reservoir of this pathogen. Salmonella control in pig production requires multiple measures amongst which vaccination ...

    • Elevated c-di-GMP levels promote biofilm formation and biodesulfurization capacity of Rhodococcus erythropolis 

      Dorado Morales, Pedro Upna Orcid; Martínez, Igor; Rivero Buceta, Virginia; Díaz, Eduardo; Bähre, Heike; Lasa Uzcudun, Íñigo Upna Orcid; Solano Goñi, Cristina Upna Orcid (Society for Applied MicrobiologyJohn Wiley & Sons, 2020)   Artículo / Artikulua  OpenAccess
      Bacterial biofilms provide high cell density and a superior adaptation and protection from stress conditions compared to planktonic cultures, making them a very promising approach for bioremediation. Several Rhodococcus ...

    • Fitness cost evolution of natural plasmids of staphylococcus aureus 

      Dorado Morales, Pedro Upna Orcid; Garcillán-Barcia, María Pilar; Lasa Uzcudun, Íñigo Upna Orcid; Solano Goñi, Cristina Upna Orcid (American Society for Microbiology, 2021)   Artículo / Artikulua  OpenAccess
      Plasmids have largely contributed to the spread of antimicrobial resistance genes among Staphylococcus strains. Knowledge about the fitness cost that plasmids confer on clinical staphylococcal isolates and the coevolutionary ...

    • The impact of two-component sensorial network in staphylococcal speciation 

      Rapún Araiz, Beatriz Upna Orcid; Haag, Andreas F.; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Elsevier, 2020)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. ...

    • Inhibiting the two‑component system GraXRS with verteporfin to combat Staphylococcus aureus infections 

      Prieto Mariscal, Juana María; Rapún Araiz, Beatriz Upna Orcid; Gil Puig, Carmen Upna Orcid; Penadés, José R.; Lasa Uzcudun, Íñigo Upna Orcid; Latasa Osta, Cristina Upna (Nature Research, 2020)   Artículo / Artikulua  OpenAccess
      Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue. With the aim of exploring a novel therapeutic approach, we chose GraXRS, a Two-Component System (TCS) that determines bacterial ...

    • A pyrene-inhibitor fluorescent probe with large stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing staphylococcus aureus biofilms 

      Mahía, Alejandro; Conde-Giménez, María; Salillas, Sandra; Pallarés, Irantzu; Galano-Frutos, Juan J.; Lasa Uzcudun, Íñigo Upna Orcid; Ventura, Salvador; Díaz-de-Villegas, María D.; Gálvez, José A.; Sancho, Javier (Springer, 2019)   Artículo / Artikulua  OpenAccess
      Amyloid fibrils formed by a variety of peptides are biological markers of different human diseases, such as Alzheimer, Parkinson or Type II diabetes, and are structural constituents of bacterial ...

    • The role of ArlRS and VraSR in regulating ceftaroline hypersusceptibility in methicillin-resistant Staphylococcus aureus 

      Villanueva San Martín, Maite Upna Orcid; Roch, Melanie; Lasa Uzcudun, Íñigo Upna Orcid; Renzoni, Adriana; Kelley, William L. (MDPI, 2021)   Artículo / Artikulua  OpenAccess
      Methicillin-resistant Staphylococcus aureus infections are a global health problem. New control strategies, including fifth-generation cephalosporins such as ceftaroline, have been developed, however rare sporadic resistance ...

    • RsaI, un ARN régulateur aux multiples facettes, module le métabolisme du pathogène opportuniste Staphylococcus aureus 

      Desgranges, Emma; Bronesky, Delphine; Corvaglia, Anna; François, Patrice; Caballero Sánchez, Carlos Upna; Prado, Laura; Toledo Arana, Alejandro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Moreau, Karen; Vandenesch, François; Marzi, Stefano; Romby, Pascale; Caldelari, Isabelle (EDP Sciences, 2019)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus est une bactérie commensale retrouvée chez environ 30 % des individus sains dont elle colonise la peau et la muqueuse nasale. Cependant, c’est également une bactérie pathogène opportuniste ...

    • Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch 

      Ma, Junfeng; Cheng, Xiang; Xu, Zhonghe; Zhang, Yikan; Valle Turrillas, Jaione Upna Orcid; Fan, Xianyang; Lasa Uzcudun, Íñigo Upna Orcid (EMBO Press, 2021)   Artículo / Artikulua  OpenAccess
      The Staphylococcal Bap proteins sense environmental signals (such as pH, [Ca2+]) to build amyloid scaffold biofilm matrices via unknown mechanisms. We here report the crystal structure of the aggregation-prone region of ...

    • A systematic evaluation of the two-component systems network reveals that ArlRS is a key regulator of catheter colonization by Staphylococcus aureus 

      Burgui Erice, Saioa Upna Orcid; Gil Puig, Carmen Upna Orcid; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid; Valle Turrillas, Jaione Upna Orcid (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the ...

    • Systematic reconstruction of the complete two-component sensorial network in staphylococcus aureus 

      Rapún Araiz, Beatriz Upna Orcid; Haag, Andreas F.; Gil Puig, Carmen Upna Orcid; Dorado Morales, Pedro Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (American Society for Microbiology, 2020)   Artículo / Artikulua  OpenAccess
      In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different ...
      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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