Listar Artículos de revista DCS - OZS Aldizkari artikuluak por título
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Cutting down on lung cancer: Ecliptasaponin A is a novel therapeutic agent
This article is a comment of 'Han J, Lv W, Sheng H, et al. Ecliptasaponin A induces apoptosis through the activation of ASK1/JNK pathway and autophagy in human lung cancer cells. Ann Transl Med 2019;7:539'. -
Cutting-edge CAR engineering: beyond T cells
Chimeric antigen receptor (CAR)-T adoptive cell therapy is one of the most promising advanced therapies for the treatment of cancer, with unprecedented outcomes in haematological malignancies. However, it still lacks ... -
Cutting-edge: preclinical and clinical development of the first approved LAG-3 inhibitor
Immune checkpoint inhibitors (ICIs) have revolutionized medical practice in oncology since the FDA approval of the first ICI 11 years ago. In light of this, Lymphocyte-Activation Gene 3 (LAG-3) is one of the most important ... -
Cytoarchitectonic areas of the gyrus ambiens in the human brain
The Gyrus ambiens is a gross anatomical prominence in the medial temporal lobe (MTL), associated closely with Brodmann area 34 (BA34). It is formed largely by the medial intermediate subfield of the entorhinal cortex (EC) ... -
Cytokines and lymphoid populations as potential biomarkers in locally and borderline pancreatic adenocarcinoma
Despite its relative low incidence, PDAC is one of the most aggressive and lethal types of cancer, being currently the seventh leading cause of cancer death worldwide, with a 5-year survival rate of 10.8%. Taking into ... -
Deciphering CHFR role in pancreatic ductal adenocarcinoma
Checkpoint with forkhead-associated and ring finger domains (CHFR) has been proposed as a predictive and prognosis biomarker for different tumor types, but its role in pancreatic ductal adenocarcinoma (PDAC) remains unknown. ... -
Deciphering the constrained total energy expenditure model in humans by associating accelerometer-measured physical activity from wrist and hip
The constrained total energy expenditure (TEE) model posits that progressive increases in physical activity (PA) lead to increases in TEE; but after certain PA threshold, TEE plateaus. Then, a compensatory reduction in the ... -
A decision tree based approach with sampling techniques to predict the survival status of poly-trauma patients
Survival prediction of poly-trauma patients measure the quality of emergency services by comparing their predictions with the real outcomes. The aim of this paper is to tackle this problem applying C4.5 since it achieves ... -
'Defining the independence of the liver circadian clock' & 'BMAL1-driven tissue clocks respond independently to light to maintain homeostasis'
These studies demonstrate that peripheral tissues and organs can detect changes in environmental light and are capable of maintaining some basic functions, independently from our brain clock. The liver can autonomously ... -
Deformaciones raquíticas de miembros inferiores en los niños congoleños
Objetivo. Analizar algunos factores de riesgo en niños raquíticos congoleños con graves deformidades de miembros inferiores y describir las lesiones. Métodos. Los autores analizaron los parámetros obtenidos en una ... -
Demografía de Mélida (Navarra) en la Edad Moderna (siglos XVII-XVIII) a partir de los Archivos Parroquiales
En este trabajo se analiza la evolución demográfica de Mélida (Navarra) durante los siglos XVII y XVIII, a partir de los libros existentes en los Archivos Parroquiales. Se estudian los factores demográficos por excelencia ... -
Density of nurses and midwives in sub-Saharan Africa: trends analysis over the period 2004-2016
Aim: to analyse the trends of density rates of nurses and midwives per population in sub-Saharan Africa over the period from 2004 to 2016. Background: nursing, the largest health care workforce, is actively contributing ... -
Deregulated transcription and proteostasis in adult mapt knockout mouse
Transcriptomics and phosphoproteomics were carried out in the cerebral cortex of B6.Cg-Mapttm1(EGFP)Klt (tau knockout: tau-KO) and wild-type (WT) 12 month-old mice to learn about the effects of tau ablation. Compared with ... -
Desafíos en la continuidad de cuidados para la práctica profesional de enfermería
La transformación de los sistemas sanitarios para dar respuesta a las necesidades del paciente crónico y pluripatológico ha situado la continuidad de cuidados como uno de los pilares en los que se basan los programas de ... -
Descripción de los ingresos y reingresos de recién nacidos prematuros en España: causas y costes
Objetivo: Identificar las principales causas de ingresos y reingresos hospitalarios de recién nascidos prematuros y evaluar los costes que los reingresos generan entre los años 2000 y 2011 en el Hospital Virgen Del Camino ... -
Design, implementation and evaluation of an education course to promote professional self-efficacy for breastfeeding care
The objective of this study was to determine the effect of an education short course on professional’ self-efficacy in the area of breastfeeding care. The intervention had a pre-post design. A total of 43 healthcare ... -
Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: identification of a Se-indomethacin analog as a potential therapeutic for breast cancer
A total of twenty-five novel carboxylic acid, methylester, methylamide or cyano nonsteroidal anti-inflammatory drug (NSAID) derivatives incorporating Se in the chemical form of selenoester were reported. Twenty Se-NSAID ... -
Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR
Background: We present two melting curve analysis (MCA)-based semiquantitative real time PCR techniques to detect the promoter methylation status of genes. The first, MCA-MSP, follows the same principle as standard MSP ... -
El deterioro funcional y la polifarmacia como predictoras de riesgo en el paciente mayor de 65 años en urgencias
Introducción y objetivo. El objetivo ha sido analizar la asociación entre el deterioro funcional y la polifarmacia del paciente anciano con la mortalidad, la frecuentación en urgencias y la hospitalización a corto plazo, ... -
Determinants of adherence to the mediterranean diet in Spanish children and adolescents: the PASOS Study
A progressive shift away from traditional healthy dietary patterns, such as the Mediterranean diet (MedDiet), has been observed in recent decades. The aim of this study was to assess determinants of optimal adherence to ...