• A diphenyldiselenide derivative induces autophagy via JNK in HTB-54 lung cancer cells 

      Díaz, Marta; González, Roncesvalles; Plano, Daniel; Palop, Juan Antonio; Sanmartín, Carmen; Encío Martínez, Ignacio Upna Orcid (Wiley, 2017)   Artículo / Artikulua  OpenAccess
      Symmetric aromatic diselenides are potential anticancer agents with strong cytotoxic activity. In this study, the in vitro anticancer activities of a novel series of diarylseleno derivatives from the diphenyldiselenide ...
    • Novel methylselenoesters as antiproliferative agents 

      Díaz Argelich, Nuria; Encío Martínez, Ignacio Upna Orcid; Plano, Daniel; Fernandes, Aristi P.; Palop, Juan Antonio; Sanmartín, Carmen (MDPI, 2017)   Artículo / Artikulua  OpenAccess
      Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this ...
    • Organoseleno cytostatic derivatives: autophagic cell death with AMPK and JNK activation 

      Garnica, Pablo; Encío Martínez, Ignacio Upna Orcid; Plano, Daniel; Palop, Juan Antonio; Sanmartín, Carmen (Elsevier Masson SAS, 2019)   Artículo / Artikulua  OpenAccess
      Selenocyanates and diselenides are potential antitumor agents. Here we report two series of selenium derivatives related to selenocyanates and diselenides containing carboxylic, amide and imide moieties. These compounds ...
    • Synthesis and pharmacological screening of several aroyl and heteroaroyl selenylacetic acid derivatives as cytotoxic and antiproliferative agents 

      Sanmartín, Carmen; Plano, Daniel; Domínguez, Enrique; Font, María; Calvo, Alfonso; Prior, Celia; Encío Martínez, Ignacio Upna Orcid; Palop, Juan Antonio (MDPI, 2009)   Artículo / Artikulua  OpenAccess
      The synthesis and cytotoxic activity of a series of twenty six aroyl and heteroaroyl selenylacetic acid derivatives of general formula Ar-CO-Se-CH(2)-COOH or Heterar-CO-Se-CH(2)-COOH are reported. The synthesis was carried ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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