Listar Artículos de revista DCS - OZS Aldizkari artikuluak por autor "Sharma, Arun K."
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Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: identification of a Se-indomethacin analog as a potential therapeutic for breast cancer
Ramos Inza, Sandra; Encío Martínez, Ignacio ; Raza, Asif; Sharma, Arun K.; Sanmartín, Carmen; Plano, Daniel (Elsevier, 2022) Artículo / ArtikuluaA total of twenty-five novel carboxylic acid, methylester, methylamide or cyano nonsteroidal anti-inflammatory drug (NSAID) derivatives incorporating Se in the chemical form of selenoester were reported. Twenty Se-NSAID ... -
New formulation of a methylseleno-aspirin analog with anticancer activity towards colon cancer
Ruberte, Ana Carolina; González Gaitano, Gustavo; Sharma, Arun K.; Aydillo, Carlos; Encío Martínez, Ignacio ; Sanmartín, Carmen; Plano, Daniel (MDPI, 2020) Artículo / ArtikuluaAspirin (ASA) has attracted wide interest of numerous scientists worldwide thanks to its chemopreventive and chemotherapeutic effects, particularly in colorectal cancer (CRC). Incorporation of selenium (Se) atom into ASA ... -
Novel acylselenourea derivatives: dual molecules with anticancer and radical scavenging activity
Astráin-Redín, Nora; Raza, Asif; Encío Martínez, Ignacio ; Sharma, Arun K.; Plano, Daniel; Sanmartín, Carmen (MDPI, 2023) Artículo / ArtikuluaOxidative stress surrounding cancer cells provides them with certain growth and survival advantages necessary for disease progression. In this context, Se-containing molecules have gained attention due to their anticancer ... -
Novel selenadiazole derivatives as selective antitumor and radical scavenging agents
Ruberte, Ana Carolina; Plano, Daniel; Encío Martínez, Ignacio ; Aydillo, Carlos; Sharma, Arun K.; Sanmartín, Carmen (Elsevier, 2018) Artículo / ArtikuluaTwenty-seven novel benzo[c][1,2,5]selenadiazole-5-carboxylic acid (BSCA) derivatives were designed and synthesized. Anti-proliferative activity of these structures was tested in vitro against a panel of five human cancer ... -
Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds
Astráin-Redín, Nora; Talavera, Irene; Moreno, Esther; Ramírez, María J.; Martínez-Sáez, Nuria; Encío Martínez, Ignacio ; Sharma, Arun K.; Sanmartín, Carmen; Plano, Daniel (MDPI, 2023) Artículo / ArtikuluaNowadays, oxidative cell damage is one of the common features of cancer and Alzheimer’s disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated ...