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The effect of a multicomponent intervention on steatosis is partially mediated by the reduction of intermuscular abdominal adipose tissue in children with overweight or obesity: the EFIGRO Project
(American Diabetes Association, 2022)
Artículo / Artikulua,
OBJECTIVE: In adults, there is evidence that improvement of metabolic-associated fatty liver disease (MAFLD) depends on the reduction of myosteatosis. In children, in whom the prevalence of MAFLD is alarming, this muscle-liver ...
Effects of a family-based lifestyle intervention plus supervised exercise training on abdominal fat depots in children with overweight or obesity: a secondary analysis of a nonrandomized clinical trial
(American Medical Association, 2022)
Artículo / Artikulua,
Importance Excess abdominal fat is a major determinant in the development of insulin resistance and other metabolic disorders. Increased visceral adipose tissue (VAT) seems to precede the development of insulin resistance ...
Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch
(EMBO Press, 2021)
info:eu-repo/semantics/article,
The Staphylococcal Bap proteins sense environmental signals (such as pH, [Ca2+]) to build amyloid scaffold biofilm matrices via unknown mechanisms. We here report the crystal structure of the aggregation-prone region of ...
Psychiatric hospitalization for attempted suicide and reattempt at the one-year follow-up
(Colegio Oficial de Psicólogos del Principado de Asturias, 2022)
Artículo / Artikulua,
Antecedentes: las personas hospitalizadas por un intento de suicidio (IS) tienen un riesgo alto de repetir/consumar el suicidio en los meses siguientes al alta. El objetivo de este estudio es comparar un tratamiento habitual ...
The role of education in executive functions, behavioral problems and functional performance in people with schizophrenia
(American Psychological Association, 2021)
info:eu-repo/semantics/article,
Objective: this cross-sectional study examined the influence of education on executive functions, behavioral problems and functional performance in people with chronic schizophrenia. Method: our sample was composed of 116 ...
Accelerated forgetting in temporal lobe epilepsy: When does it occur?
(Elsevier, 2021)
info:eu-repo/semantics/article,
Objective: the main goal of the study was to analyse differences in the forgetting rates of Temporal Lobe Epilepsy (TLE) patients at different intervals (30 sec, 10 min, 1 day and 1 week) compared with those of healthy ...
PD-L1 as a prognostic factor in early-stage colon carcinoma within the immunohistochemical molecular subtype classification
(MDPI, 2021)
Artículo / Artikulua,
Colorectal cancer (CRC) is a very heterogeneous disease. Efforts to characterize and search for biomarkers for these patients are currently ongoing in the hope of establishing a more targeted therapeutic approach. The role ...
Development of a prediction protocol for the screening of metabolic associated fatty liver disease in children with overweight or obesity
(Wiley, 2022)
Artículo / Artikulua,
Background: the early detection and management of children with metabolic associ-ated fatty liver disease (MAFLD) is challenging. Objective: to develop a non-invasive and accurate prediction protocol for the identi-fication ...
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity
(Rockefeller University Press, 2022)
Artículo / Artikulua,
Lung cancer remains the leading cause of cancer-related death worldwide. We identify DSTYK, a dual serine/threonine and tyrosine non-receptor protein kinase, as a novel actionable target altered in non-small cell lung ...
Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial
(BMC, 2022)
Artículo / Artikulua,
Background: Falls represent important drivers of intrinsic capacity losses, functional limitations and reduced quality of life in the growing older adult’s population, especially among those presenting with frailty. Despite ...