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Role of sodium salicylate in Staphylococcus aureus quorum sensing, virulence, biofilm formation and antimicrobial susceptibility
(Frontiers Media, 2022)
Artículo / Artikulua,
The widespread threat of antibiotic resistance requires new treatment options. Disrupting bacterial communication, quorum sensing (QS), has the potential to reduce pathogenesis by decreasing bacterial virulence. The aim ...
Analysis of the association between polymorphisms in intergenic regions of Staphylococcus aureus genes involved in biofilm formation and periprosthetic joint infections
(2022)
info:eu-repo/semantics/doctoralThesis,
In this thesis, we have focused on studying variants found in IGRs adjacent to the most important genes involved in S. aureus biofilm formation; the icaADBCR locus, and the genes encoding the family of surface adhesins. ...
Genetic reductionist approach for studing the two-component signaling system in Staphylococcus aureus
(2014)
info:eu-repo/semantics/doctoralThesis,
Staphylococcus aureus es una bacteria ubicua capaz de colonizar una gran variedad de ambientes. En el hombre, S. aureus coloniza las fosas nasales, piel de las axilas, ingles, garganta o incluso el tracto intestinal. Se ...
Functional analysis of intergenic regulatory regions of genes encoding surface adhesins in Staphylococcus aureus isolates from periprosthetic joint infections
(Elsevier, 2022)
Artículo / Artikulua,
Staphylococcus aureus is a leading cause of prosthetic joint infections (PJI). Surface adhesins play an important
role in the primary attachment to plasma proteins that coat the surface of prosthetic devices after ...
Evaluación microbiológica de la higiene de manos de los profesionales de las ambulancias de emergencia en Navarra
(Asociación de Especialistas en Enfermería del Trabajo, 2019)
info:eu-repo/semantics/article,
Introducción. Las superficies de las ambulancias están frecuentemente contaminadas por microorganismos debido principalmente a deficiencias tanto en la limpieza de las mismas como la observación de las medidas básicas de ...
Bacterial biofilm functionalization through Bap amyloid engineering
(Springer Nature, 2022)
Artículo / Artikulua,
Biofilm engineering has emerged as a controllable way to fabricate living structures with programmable functionalities. The amyloidogenic proteins comprising the biofilms can be engineered to create self-assembling ...
RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
Staphylococcus aureus susceptibility to complestatin and corbomycin depends on the VraSR two-component system
(American Society for Microbiology, 2023)
Artículo / Artikulua,
The overuse of antibiotics in humans and livestock has driven the emergence and spread of antimicrobial resistance and has therefore prompted research
on the discovery of novel antibiotics. Complestatin (Cm) and corbomycin ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
