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Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals
(Public Library of Science, 2016)
Artículo / Artikulua,
Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
Genome-wide antisense transcription drives mRNA processing in bacteria
(National Academy of Sciences, 2011)
Artículo / Artikulua,
RNA deep sequencing technologies are revealing unexpected levels of complexity in bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs, long 5′ and 3′ untranslated regions, and alternative ...
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
(Public Library of Science, 2012)
Artículo / Artikulua,
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence
structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ...
RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence
factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation
capacity ...
SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
Staphylococcus epidermidis biofilm formation is associated with the production of the polysaccharide intercellular
adhesin (PIA)--poly-N-acetylglucosamine polysaccharide (PNAG) by the products of the icaADBC
operon. ...
SarA positively controls Bap-dependent biofilm formation in Staphylococcus aureus
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
The biofilm-associated protein Bap is a staphylococcal surface protein involved in biofilm formation. We
investigated the influence of the global regulatory locus sarA on bap expression and Bap-dependent biofilm
formation ...
Beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus
(American Society for Microbiology, 2006)
info:eu-repo/semantics/article,
Antibiotics that interfere with DNA replication and cell viability activate the SOS response. In Staphylococcus
aureus, the antibiotic-induced SOS response promotes replication and high-frequency horizontal transfer ...
Sensory deprivation in Staphylococcus aureus
(Springer Nature, 2018)
info:eu-repo/semantics/article,
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16
TCSs, one of which (WalRK) is essential. Here we show ...
B regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variation
(American Society for Microbiology, 2007)
info:eu-repo/semantics/article,
Biofilm formation in Staphylococcus aureus is subject to phase variation, and biofilm-negative derivatives emerge sporadically from a biofilm-positive bacterial population. To date, the only known mechanism for generating ...