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RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria
(Oxford University Press, 2011)
Artículo / Artikulua,
Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria
(Oxford University Press, 2013)
info:eu-repo/semantics/article,
The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...
Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands
(Nature Research, 2010)
info:eu-repo/semantics/article,
Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ...
Role of biofilm-associated protein bap in the pathogenesis of bovine Staphylococcus aureus
(American Society for Microbiology, 2004)
info:eu-repo/semantics/article,
Staphylococcus aureus is a common cause of intramammary infections, which frequently become chronic, associated with the ability of the bacteria to produce biofilm. Here, we report a relationship between the ability to ...
Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer
(American Society for Microbiology, 2007)
info:eu-repo/semantics/article,
SaPIbov2 is a member of the SaPI family of staphylococcal pathogenicity islands and is very closely related to SaPIbov1. Typically, certain temperate phages can induce excision and replication of one or more of these islands ...
Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process
(American Society for Microbiology, 2002)
info:eu-repo/semantics/article,
The adherence of Staphylococcus aureus to soluble proteins and extracellular-matrix components of the host is one of the key steps in the pathogenesis of staphylococcal infections. S. aureus presents a family of adhesins ...
SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development
(American Society for Microbiology, 2005)
info:eu-repo/semantics/article,
Staphylococcus epidermidis biofilm formation is associated with the production of the polysaccharide intercellular
adhesin (PIA)--poly-N-acetylglucosamine polysaccharide (PNAG) by the products of the icaADBC
operon. ...
Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins
(American Society for Microbiology, 2008)
info:eu-repo/semantics/article,
Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ...