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Inactivation of the Thymidylate synthase thyA in non-typeable Haemophilus influenzae modulates antibiotic resistance and has a strong impact on its interplay with the host airways
(Frontiers Media, 2017)
info:eu-repo/semantics/article,
Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate ...
Transformed recombinant enrichment profiling rapidly identifies HMW1 as an intracellular invasion locus in Haemophilus influenzae
(Public Library of Science, 2016)
info:eu-repo/semantics/article,
Many bacterial species actively take up and recombine homologous DNA into their genomes,
called natural competence, a trait that offers a means to identify the genetic basis of naturally
occurring phenotypic variation. ...
Resveratrol therapeutics combines both antimicrobial and immunomodulatory properties against respiratory infection by nontypeable Haemophilus influenzae
(Springer Nature, 2017)
info:eu-repo/semantics/article,
The respiratory pathogen nontypeable Haemophilus influenzae (NTHi) is an important cause of acute
exacerbation of chronic obstructive pulmonary disease (AECOPD) that requires efficient treatments.
A previous screening ...
Antagonistic pleiotropy in the bifunctional surface protein fadl (OmpP1) during adaptation of Haemophilus influenzae to chronic lung infection associated with chronic obstructive pulmonary disease
(American Society for Microbiology, 2018)
info:eu-repo/semantics/article,
Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects ...
Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways
(Springer, 2018)
info:eu-repo/semantics/article,
Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in ...