• The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice 

      San Román Aberasturi, Beatriz Upna; Lasa Uzcudun, Íñigo Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Lasarte, Juan José; Grilló Dolset, María Jesús; Garrido, Victoria Upna; Muñoz Álvaro, Pilar María; Arribillaga, Laura; García Martínez, Begoña Upna; Andrés, Ximena de; Zabaleta, Virginia Upna; Mansilla, Cristina; Farrán Blanch, Inmaculada Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
    • Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection 

      Crespo, Helena Upna; Reina Arias, Ramsés Upna; Glaría Ezquer, Idoia Upna; Ramírez, Hugo Upna; Andrés, Ximena de; Jauregui, Paula; Luján, Lluís; Martínez Pomares, Luisa; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2011)   Artículo / Artikulua  OpenAccess
      This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...
    • Mannose receptor may be involved in small ruminant lentivirus pathogenesis 

      Crespo, Helena Upna; Jauregui, Paula; Glaría Ezquer, Idoia Upna; Sanjosé, Leticia; Polledo, Laura; García Marín, Juan F.; Luján, Lluís; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Reina Arias, Ramsés Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
    • Post-entry blockade of small ruminant lentiviruses by wild ruminants 

      Sanjosé, Leticia; Crespo, Helena Upna; Blatti-Cardinaux, Laure; Glaría Ezquer, Idoia Upna; Martínez Carrasco, Carlos; Berriatua, Eduardo; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna; Bertoni, Giuseppe; Reina Arias, Ramsés Upna (BioMed Central, 2016)   Artículo / Artikulua  OpenAccess
      Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
    • Small ruminant macrophage polarization may play a pivotal role on lentiviral infection 

      Crespo, Helena Upna; Bertolotti, Luigi; Juganaru, Magda; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Rosati, Sergio; Reina Arias, Ramsés Upna (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
    • Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Bertolotti, Luigi; Cenoz, Amaia Upna; Hernández, Mirna Margarita; San Román Aberasturi, Beatriz Upna; Glaría Ezquer, Idoia Upna; Andrés, Ximena de; Crespo, Helena Upna; Jauregui, Paula; Benavides, Julio; Polledo, Laura; Pérez, Valentín; García Marín, Juan F.; Rosati, Sergio; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...