Listar Artículos de revista IdAB - IdAB Aldizkari artikuluak por autor UPNA "Lasa Uzcudun, Íñigo"
Mostrando ítems 1-20 de 45
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Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli
Moreno Bruna, Beatriz
; Baroja Fernández, Edurne 
; Muñoz Pérez, Francisco José ; Bastarrica Berasategui, Ainara ; Zandueta Criado, Aitor ; Rodríguez López, Milagros ; Lasa Uzcudun, Íñigo ; Akazawa, Takashi; Pozueta Romero, Javier (National Academy of Sciences, 2001)
Artículo / Artikulua 
An adenosine diphosphate sugar pyrophosphatase (ASPPase, EC 3.6.1.21) has been characterized by using Escherichia coli. This enzyme, whose activities in the cell are inversely correlated with the intracellular glycogen ... -
Amyloid structures as biofilm matrix scaffolds
Taglialegna, Agustina; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione (American Society for Microbiology, 2016)
Artículo / Artikulua
Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward the recognition of amyloid fibers as common building block structures that confer stability to the exopolysaccharide matrix. ... -
B regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variation
Valle Turrillas, Jaione ; Vergara Irigaray, Marta ; Merino, Nekane ; Penadés, José R.; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2007)
Artículo / Artikulua
Biofilm formation in Staphylococcus aureus is subject to phase variation, and biofilm-negative derivatives emerge sporadically from a biofilm-positive bacterial population. To date, the only known mechanism for generating ... -
Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor
Valle Turrillas, Jaione ; Latasa Osta, Cristina ; Gil Puig, Carmen ; Toledo Arana, Alejandro ; Solano Goñi, Cristina ; Penadés, José R.; Lasa Uzcudun, Íñigo (Public Library of Science, 2012)
Artículo / Artikulua
The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, ... -
Bap, a Staphylococcus aureus surface protein involved in biofilm formation
Cucarella, Carme; Solano Goñi, Cristina ; Valle Turrillas, Jaione ; Amorena Zabalza, Beatriz ; Lasa Uzcudun, Íñigo ; Penadés, José R. (American Society for Microbiology, 2001)
Artículo / Artikulua
Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain variation and the pathogenic mechanisms implicated in chronic staphylococcal infections. A biofilm-producing ... -
Base pairing interaction between 5′- and 3′-UTRs controls icaR mRNA translation in Staphylococcus aureus
Ruiz de los Mozos Aliaga, Igor; Vergara Irigaray, Marta ; Segura, Víctor; Villanueva San Martín, Maite ; Bitarte, Nerea ; Saramago, Margarida; Domingues, Susana; Arraiano, Cecilia M.; Fechter, Pierre; Romby, Pascale; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro (Public Library of Science, 2013)
Artículo / Artikulua
The presence of regulatory sequences in the 39 untranslated region (39-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized. In contrast, the relevance of 39-UTRs in bacterial ... -
Beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus
Maiques, Elisa; Ubeda, Carles; Campoy Sánchez, Susana; Salvador, Noelia; Lasa Uzcudun, Íñigo ; Novick, Richard P.; Barbé, Jordi; Penadés, José R. (American Society for Microbiology, 2006)
Artículo / Artikulua
Antibiotics that interfere with DNA replication and cell viability activate the SOS response. In Staphylococcus aureus, the antibiotic-induced SOS response promotes replication and high-frequency horizontal transfer ... -
Biofilm dispersion and quorum sensing
Solano Goñi, Cristina ; Echeverz Sarasúa, Maite ; Lasa Uzcudun, Íñigo (Elsevier, 2014)
Artículo / Artikulua
Biofilm development and quorum sensing are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self produced extracellular matrix. ... -
Biofilm matrix exoproteins induce a protective immune response against Staphylococcus aureus biofilm infection
Gil Puig, Carmen ; Solano Goñi, Cristina ; Burgui Erice, Saioa ; Latasa Osta, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo ; Valle Turrillas, Jaione (American Society for Microbiology, 2014)
Artículo / Artikulua
The Staphylococcus aureus biofilm mode of growth is associated with several chronic infections that are very difficult to treat due to the recalcitrant nature of biofilms to clearance by antimicrobials. Accordingly, there ... -
Biofilm switch and immune response determinants at early stages of infection
Valle Turrillas, Jaione ; Solano Goñi, Cristina ; García Martínez, Begoña ; Toledo Arana, Alejandro ; Lasa Uzcudun, Íñigo (Elsevier (Cell Press), 2013)
Artículo / Artikulua
Biofilm development is recognized as a major virulence factor underlying most chronic bacterial infections. When a biofilm community is established, planktonic cells growing in the surroundings of a tissue switch to a ... -
Calcium inhibits bap-dependent multicellular behavior in Staphylococcus aureus
Arrizubieta Balerdi, María Jesús; Toledo Arana, Alejandro ; Amorena Zabalza, Beatriz ; Penadés, José R.; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2004)
Artículo / Artikulua
Bap (biofilm-associated protein) is a 254-kDa staphylococcal surface protein implicated in formation of biofilms by staphylococci isolated from chronic mastitis infections. The presence of potential EF-hand motifs in the ... -
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate
Pérez, Astrid; Canle, Delia; Latasa Osta, Cristina; Poza, Margarita; Beceiro, Alejandro; Tomás, María del Mar; Fernández, Ana; Mallo, Susana; Pérez, Sonia; Molina, Francisca; Villanueva González, Rosa; Lasa Uzcudun, Íñigo ; Bou, Germán (American Society for Microbiology, 2007)
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Enterobacter cloacae is an emerging clinical pathogen that may be responsible for nosocomial infections. Management of these infections is often difficult, owing to the high frequency of strains that are resistant to ... -
Conditional mutation of an essential putative glycoprotease eliminates autolysis in Staphylococcus aureus
Zheng, L.; Yu, C.; Bayles, K.; Lasa Uzcudun, Íñigo ; Ji, Y. (American Society for Microbiology, 2007)
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Our previous studies demonstrated that a putative Staphylococcus aureus glycoprotease (Gcp) is essential for bacterial survival, indicating that Gcp may be a novel target for developing antibacterial agents. However, the ... -
Coordinated cyclic-di-GMP repression of salmonella motility through YcgR and cellulose
Zorraquino Salvo, Violeta; García Martínez, Begoña ; Latasa Osta, Cristina ; Echeverz Sarasúa, Maite ; Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina (American Society for Microbiology, 2013)
Artículo / Artikulua
Cyclic di-GMP (c-di-GMP) is a secondary messenger that controls a variety of cellular processes, including the switch between a biofilm and a planktonic bacterial lifestyle. This nucleotide binds to cellular effectors in ... -
Effect of transcriptional activators SoxS, RobA, and RamA on expression of multidrug efflux pump AcrAB-TolC in enterobacter cloacae
Pérez, Astrid; Poza, Margarita; Aranda, Jesús; Latasa Osta, Cristina; Medrano, Francisco Javier; Tomás, María del Mar; Romero, Antonio; Lasa Uzcudun, Íñigo ; Bou, Germán (American Society for Microbiology, 2012)
Artículo / Artikulua
Control of membrane permeability is a key step in regulating the intracellular concentration of antibiotics. Efflux pumps confer innate resistance to a wide range of toxic compounds such as antibiotics, dyes, detergents, ... -
An effort to make sense of antisense transcription in bacteria
Lasa Uzcudun, Íñigo ; Toledo Arana, Alejandro ; Gingeras, Thomas R. (Taylor & Francis, 2012)
Artículo / Artikulua
Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some ... -
The enterococcal surface protein, Esp, is involved in Enterococcus faecalis biofilm formation
Toledo Arana, Alejandro ; Valle Turrillas, Jaione ; Solano Goñi, Cristina ; Arrizubieta Balerdi, María Jesús ; Cucarella, Carme; Lamata, Marta; Amorena Zabalza, Beatriz ; Leiva, José; Penadés, José R.; Lasa Uzcudun, Íñigo (American Society for Microbiology, 2001)
Artículo / Artikulua
The enterococcal surface protein, Esp, is a high-molecular-weight surface protein of unknown function whose frequency is significantly increased among infection-derived Enterococcus faecalis isolates. In this work, a ... -
Evaluation of a Salmonella strain lacking the secondary messenger c-di-GMP and RpoS as a live oral vaccine
Latasa Osta, Cristina; Echeverz Sarasúa, Maite ; García Ona, Enrique ; Burgui Erice, Saioa ; Casares, Noelia; Hervás Stubbs, Sandra ; Lasarte, Juan José; Lasa Uzcudun, Íñigo ; Solano Goñi, Cristina ; García Martínez, Begoña ; Gil Puig, Carmen (Public Library of Science, 2016)
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Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food, with chicken and pig related products being key reservoirs of infection. Although numerous ... -
Evaluation of surface microtopography engineered by direct laser interference for bacterial anti-biofouling
Valle Turrillas, Jaione ; Burgui Erice, Saioa ; Langheinrich, Denise; Gil Puig, Carmen ; Solano Goñi, Cristina ; Toledo Arana, Alejandro ; Helbig, Ralf; Lasagni, Andrés; Lasa Uzcudun, Íñigo (2015)
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Biofilm formation by bacterial pathogens on the surface of medical and industrial settings is a 25 serious health problem. Modification of the biomaterial surface topography is a promising 26 strategy to prevent bacterial ... -
Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process
Cucarella, Carme; Tormo Más, María Ángeles; Knecht, Erwin; Amorena Zabalza, Beatriz; Lasa Uzcudun, Íñigo ; Foster, Timothy J.; Penadés, José R. (American Society for Microbiology, 2002)
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The adherence of Staphylococcus aureus to soluble proteins and extracellular-matrix components of the host is one of the key steps in the pathogenesis of staphylococcal infections. S. aureus presents a family of adhesins ...
