Now showing items 77-96 of 158

    • Inactivation of the Thymidylate synthase thyA in non-typeable Haemophilus influenzae modulates antibiotic resistance and has a strong impact on its interplay with the host airways 

      Rodríguez Arce, Irene; Martí, Sara; Euba, Begoña; Fernández Calvet, Ariadna; Moleres Apilluelo, Javier; López López, Nahikari; Barberán, Montserrat; Ramos Vivas, José; Tubau, Fe; Losa, Carmen; Ardanuy, Carmen; Leiva, José; Yuste, José E.; Garmendia García, Juncal (Frontiers Media, 2017)   Artículo / Artikulua  OpenAccess
      Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate ...
    • Increased bioethanol production from commercial tobacco cultivars overexpressing thioredoxin f grown under field conditions 

      Farrán Blanch, Inmaculada Upna; Fernández San Millán, Alicia Upna; Ancín Rípodas, María Upna; Larraya Reta, Luis María Upna; Veramendi Charola, Jon Upna (Springer, 2014)   Artículo / Artikulua  OpenAccess
      Bioethanol is mainly produced from food crops such as sugar cane and maize while it has been held partly responsible for the rise of food commodity prices. Tobacco, integrated in biorefinery facilities for the extraction ...
    • Increased biofilm formation by nontypeable Haemophilus influenzae isolates from patients with invasive disease or otitis media versus strains recovered from cases of respiratory infections 

      Puig, Carmen Upna; Domenech, Arnau; Garmendia García, Juncal; Langereis, Jeroen D.; Mayer, Pascal; Calatayud, Laura; Liñares, Josefina; Ardanuy, Carmen; Martí, Sara (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
      Biofilm formation by nontypeable (NT) Haemophilus influenzae remains a controversial topic. Nevertheless, biofilm-like structures have been observed in the middle-ear mucosa of experimental chinchilla models of otitis media ...
    • Intra- and intergenerational persistence of an insect nucleopolyhedrovirus: adverse effects of sublethal disease on host development, reproduction, and susceptibility to superinfection 

      Cabodevilla de Andrés, Oihana; Villar, Eduardo; Virto Garayoa, Cristina Upna; Murillo Pérez, Rosa Upna; Williams, Trevor Upna; Caballero Murillo, Primitivo Upna (American Society for Microbiology, 2011)   Artículo / Artikulua  OpenAccess
      Sublethal infections by Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) are common in field populations of the beet armyworm (S. exigua, Hübner) in the Almerian horticultural region of Spain. Inoculation of ...
    • Isotopic composition of maize as related to N-fertilization and irrigation in the Mediterranean region 

      Lasa Larrea, Berta; Irañeta, Iosu; Muro Erreguerena, Julio Upna; Irigoyen Iriarte, Ignacio Upna; Aparicio Tejo, Pedro María Upna (Escola Superior de Agricultura "Luiz de Queiroz", Universidade de São Paulo, 2011)   Artículo / Artikulua  OpenAccess
      Nitrate leaching as a result of excessive application of N-fertilizers and water use is a major problem of vulnerable regions. The farming of maize requires high N fertilization and water inputs in Spain. Isotopic ...
    • Killing niche competitors by remote-control bacteriophage induction 

      Selva, Laura; Viana, David; Regev Yochay, Gili; Trzcinski, Krzysztof; Corpa, Juan Manuel; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Penadés, José R. (National Academy of Sciences, 2009)   Artículo / Artikulua  OpenAccess
      A surprising example of interspecies competition is the production by certain bacteria of hydrogen peroxide at concentrations that are lethal for others. A case in point is the displacement of Staphylococcus aureus by ...
    • Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells 

      March, Catalina; Moranta, David; Regueiro, Verónica; Llobet, Enrique; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Biochemistry and Molecular Biology, 2011)   Artículo / Artikulua  OpenAccess
      Outer membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated Gram-negative pathogen. It is an important cause ...
    • Lacanobia oleracea nucleopolyhedrovirus (LaolNPV): a new European species of alphabaculovirus with a narrow host range 

      Simón de Goñi, Oihane; Erlandson, Martin A.; Frayssinet, Marie; Williams, Trevor Upna; Theilmann, David A.; Volkoff, Anne Nathalie; Caballero Murillo, Primitivo Upna (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      During an insect sampling program in alfalfa crops near Montpellier, France in 2011, Lacanobia oleracea larvae were collected that died due to nucleopolyhedrovirus infection (LaolNPV). This virus was subjected to molecular ...
    • Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers 

      Salazar, Eider; Berriatua, Eduardo; Pérez, Marta; Marín, Belén; Acín, Cristina; Martín Burriel, Inmaculada; Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)   Artículo / Artikulua  OpenAccess
      The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and ...
    • Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host 

      Echeverz Sarasúa, Maite Upna; García Martínez, Begoña Upna; Sabalza Baztán, Amaia; Valle Turrillas, Jaione Upna; Gabaldón Estevan, Juan Antonio; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      Many bacteria build biofilm matrices using a conserved exopolysaccharide named PGA or PNAG (poly-β-1,6-N-acetyl-D-glucosamine). Interestingly, while E. coli and other members of the family Enterobacteriaceae encode the ...
    • Leaf δ15N as a physiological indicator of the responsiveness of N2-fixing alfalfa plants to elevated CO2, temperature and low water availability 

      Ariz, Idoia Upna; Cruz, Cristina; Neves, Tomé; Irigoyen, J. Juan; García Olaverri, Carmen Upna; Nogués, Salvador; Aparicio Tejo, Pedro María Upna; Aranjuelo Michelena, Iker (Frontiers Media, 2015)   Artículo / Artikulua  OpenAccess
      The natural 15N/14N isotope composition (δ15N) of a tissue is a consequence of its N source and N physiological mechanisms in response to the environment. It could potentially be used as a tracer of N metabolism in plants ...
    • Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit 

      Crespo, Helena Upna; Guillén, Hugo; Pablo Maiso, Lorena de; Gómez Arrebola, Carmen; Rodríguez, Gregorio; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna; Reina Arias, Ramsés Upna (Taylor & Francis, 2017)   Artículo / Artikulua  OpenAccess
      β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero-Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • Maedi-visna virus infection of ovine mammary epithelial cells 

      Bolea, Rosa; Monleón, Eva; Carrasco, Librado; Vargas, Antonia; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (EDP Sciences, 2006)   Artículo / Artikulua  OpenAccess
      The aim of this work was to perform a complete study of maedi-visna virus (MVV) infected mammary glands of naturally-infected sheep, and to determine if cells other than macrophages undergo a productive viral infection in ...
    • Mannose receptor may be involved in small ruminant lentivirus pathogenesis 

      Crespo, Helena Upna; Jauregui, Paula; Glaría Ezquer, Idoia Upna; Sanjosé, Leticia; Polledo, Laura; García Marín, Juan F.; Luján, Lluís; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Reina Arias, Ramsés Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
    • Mechanisms of ammonium toxicity and the quest for tolerance 

      Esteban Terradillos, Raquel; Ariz, Idoia Upna; Cruz, Cristina; Morán Juez, José Fernando Upna (Elsevier, 2016)   Artículo / Artikulua  OpenAccess
      Ammonium sensitivity of plants is a worldwide problem, constraining crop production. Prolonged application of ammonium as the sole nitrogen source may result in physiological and morphological disorders that lead to decreased ...
    • Mixtures of complete and pif1- and pif2-deficient genotypes are required for increased potency of an insect nucleopolyhedrovirus 

      Clavijo Palacios, Gabriel; Williams, Trevor Upna; Simón de Goñi, Oihane; Muñoz, Delia Upna; Cerutti, Martine; López Ferber, Miguel; Caballero Murillo, Primitivo Upna (American Society for Microbiology, 2009)   Artículo / Artikulua  OpenAccess
      The insecticidal potency of a nucleopolyhedrovirus population (SfNIC) that infects Spodoptera frugiperda (Lepidoptera) is greater than the potency of any of the component genotypes alone. Occlusion bodies (OBs) produced ...
    • Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella 

      Insua, José Luis; Llobet, Enrique; Moranta, David; Pérez Gutiérrez, Camino; Tomás, Anna; Garmendia García, Juncal; Bengoechea, José A. (American Society for Microbiology, 2013)   Artículo / Artikulua  OpenAccess
      The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ...
    • Molecular and insecticidal characterization of a novel cry-related protein from bacillus thuringiensis toxic against Myzus persicae 

      Palma Dovis, Leopoldo Upna; Muñoz Labiano, Delia; Berry, Colin; Murillo Martínez, Jesús Upna; Escudero, Iñigo de; Caballero Murillo, Primitivo Upna (MDPI, 2014)   Artículo / Artikulua  OpenAccess
      This study describes the insecticidal activity of a novel Bacillus thuringiensis Cry-related protein with a deduced 799 amino acid sequence (~89 kDa) and ~19% pairwise identity to the 95-kDa-aphidicidal protein (sequence ...
    • Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing 

      Varela Martínez, Endika; Abendaño, Naiara; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta María; Reina Arias, Ramsés Upna; Andrés Cara, Damián de Upna; Luján, Lluís; Jugo, Begoña M. (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...