• Sensitivity of the ISO 6579:2002/Amd 1:2007 standard method for detection of Salmonella spp. on mesenteric lymph nodes from slaughter pigs 

      Mainar Jaime, Raúl Carlos; Andrés, S.; Vico, J. P.; San Román Aberasturi, Beatriz Upna; Garrido, Victoria Upna; Grilló Dolset, María Jesús (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The ISO 6579:2002/Amd 1:2007 (ISO) standard has been the bacteriological standard method used in the European Union for the detection of Salmonella spp. in pig mesenteric lymph nodes (MLN), but there are no published ...
    • Sensory deprivation in Staphylococcus aureus 

      Villanueva San Martín, Maite Upna; García Martínez, Begoña Upna; Valle Turrillas, Jaione Upna; Rapún Araiz, Beatriz; Ruiz de los Mozos Aliaga, Igor Upna; Solano Goñi, Cristina Upna; Martí, Miguel; Penadés, José R.; Toledo Arana, Alejandro Upna; Lasa Uzcudun, Íñigo Upna (Springer Nature, 2018)   Artículo / Artikulua  OpenAccess
      Bacteria use two-component systems (TCSs) to sense and respond to environmental changes. The core genome of the major human pathogen Staphylococcus aureus encodes 16 TCSs, one of which (WalRK) is essential. Here we show ...
    • Sequence diversity of rulA among natural isolates of Pseudomonas syringae and effect on function of rulAB-mediated UV radiation tolerance 

      Sundin, George W.; Jacobs, Janette L.; Murillo Martínez, Jesús Upna (American Society for Microbiology, 2000)   Artículo / Artikulua  OpenAccess
      The rulAB locus confers tolerance to UV radiation and is borne on plasmids of the pPT23A family in Pseudomonas syringae. We sequenced 14 rulA alleles from P. syringae strains representing seven pathovars and found sequence ...
    • Sf29 Gene of Spodoptera frugiperda multiple nucleopolyhedrovirus is a viral factor that determines the number of virions in occlusion bodies 

      Simón de Goñi, Oihane; Williams, Trevor Upna; Asensio, Aarón C.; Ros Terés, Sarhay; Gaya Cacho, Andrea; Caballero Murillo, Primitivo Upna; Possee, Robert D. (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      The genome of Spodoptera frugiperda multiple nucleopolyhedrovirus (NPV) was inserted into a bacmid (Sfbac) and used to produce a mutant lacking open reading frame 29 (Sf29null). Sf29null bacmid DNA was able to generate ...
    • The sf32 unique gene of spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) is a non-essential gene that could be involved in nucleocapsid organization in occlusion-derived virions 

      Beperet Arive, Inés Upna; Barrera Cubillos, Gloria Patricia; Simón de Goñi, Oihane; Williams, Trevor Upna; López Ferber, Miguel; Gasmi, Laila; Herrero, Salvador; Caballero Murillo, Primitivo Upna (Public Library of Science, 2013)   Artículo / Artikulua  OpenAccess
      A recombinant virus lacking the sf32 gene (Sf32null), unique to the Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV), was generated by homologous recombination from a bacmid comprising the complete viral genome ...
    • Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs 

      Garrido, Victoria Upna; Sánchez Alarcón, Samanta Rita; San Román Aberasturi, Beatriz Upna; Zabalza Baranguá, Ana Upna; Díaz Tendero, Yasmín; Frutos, Cristina de; Mainar Jaime, Raúl Carlos; Grilló Dolset, María Jesús (BioMed Central, 2014)   Artículo / Artikulua  OpenAccess
      Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis ...
    • Small ruminant lentiviruses: genetic variability, tropism and diagnosis 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna; Martínez, Humberto A. (MDPI, 2013)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV) cause a multisystemic chronic disease affecting animal production and welfare. SRLV infections are spread across the world with the exception of Iceland. Success in controlling SRLV spread ...
    • Small ruminant macrophage polarization may play a pivotal role on lentiviral infection 

      Crespo, Helena Upna; Bertolotti, Luigi; Juganaru, Magda; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Rosati, Sergio; Reina Arias, Ramsés Upna (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
    • Spatial distribution and risk factors of brucellosis in Iberian wild ungulates 

      Muñoz Álvaro, Pilar María; Boadella, Mariana; Arnal, Maricruz; Miguel, María Jesús de; Revilla, Miguel; Martínez, David; Vicente, Joaquín; Acevedo, Pelayo; Oleaga, Álvaro; Ruiz Fons, Francisco; Marín, Clara M.; Prieto, José M.; Fuente, José de la; Barral, Marta; Barberán, Montserrat; Fernández de Luco, Daniel; Blasco, José María Upna; Gortázar, Christian (BioMed Central, 2010)   Artículo / Artikulua  OpenAccess
      Background: The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribution ...
    • Stability of a Spodoptera frugiperda nucleopolyhedrovirus deletion recombinant during serial passage in insects 

      Simón de Goñi, Oihane; Williams, Trevor Upna; Possee, Robert D.; López Ferber, Miguel; Caballero Murillo, Primitivo Upna (American Society for Microbiology, 2009)   Artículo / Artikulua  OpenAccess
      The stabilities of the Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) complete genome bacmid (Sfbac) and a deletion recombinant (Sf29null) in which the Sf29 gene was replaced by a kanamycin resistance ...
    • Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

      Taglialegna, Agustina Upna; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
      Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
    • Staphylococcus aureus develops an alternative, ica-independent biofilm in the absence of the arlRS two-component system 

      Toledo Arana, Alejandro Upna; Merino, Nekane; Vergara Irigaray, Marta Upna; Débarbouillé, Michel; Penadés, José R.; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2005)   Artículo / Artikulua  OpenAccess
      The biofilm formation capacity of Staphylococcus aureus clinical isolates is considered an important virulence factor for the establishment of chronic infections. Environmental conditions affect the biofilm formation capacity ...
    • Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins 

      Tormo Más, María Ángeles; Ferrer, María Desamparados; Maiques, Elisa; Ubeda, Carles; Selva, Laura; Lasa Uzcudun, Íñigo Upna; Calvete, Juan J.; Novick, Richard P.; Penadés, José R. (American Society for Microbiology, 2008)   Artículo / Artikulua  OpenAccess
      Staphylococcus aureus pathogenicity islands (SaPIs) have an intimate relationship with temperate staphylococcal phages. During phage growth, SaPIs are induced to replicate and are efficiently encapsidated into special small ...
    • Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Bertolotti, Luigi; Cenoz, Amaia Upna; Hernández, Mirna Margarita; San Román Aberasturi, Beatriz Upna; Glaría Ezquer, Idoia Upna; Andrés, Ximena de; Crespo, Helena Upna; Jauregui, Paula; Benavides, Julio; Polledo, Laura; Pérez, Valentín; García Marín, Juan F.; Rosati, Sergio; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
    • Sucrose synthase activity in the sus1/sus2/sus3/sus4 Arabidopsis mutant is sufficient to support normal cellulose and starch production 

      Baroja Fernández, Edurne Upna; Muñoz Pérez, Francisco José; Li, Jun; Bahaji, Abdellatif; Almagro Zabalza, Goizeder Upna; Montero Macarro, Manuel Upna; Etxeberria, Ed; Hidalgo Cruz, Maite; Sesma Pascual, María Teresa Upna; Pozueta Romero, Javier Upna (National Academy of Sciences, 2011)   Artículo / Artikulua  OpenAccess
      Sucrose synthase (SUS) catalyzes the reversible conversion of sucrose and a nucleoside diphosphate into the corresponding nucleoside diphosphate-glucose and fructose. In Arabidopsis, a multigene family encodes six SUS ...
    • A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria 

      Quiles Puchalt, Nuria; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Toledo Arana, Alejandro Upna; Monedero, Vicente; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2013)   Artículo / Artikulua  OpenAccess
      The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families ...
    • Superinfection exclusion in alphabaculovirus infections is concomitant with actin reorganization 

      Beperet Arive, Inés Upna; Irons, Sarah L.; Simón de Goñi, Oihane; King, Linda A.; Williams, Trevor Upna; Possee, Robert D.; López Ferber, Miguel; Caballero Murillo, Primitivo Upna (American Society for Microbiology, 2014)   Artículo / Artikulua  OpenAccess
      Superinfection exclusion is the ability of an established virus to interfere with a second virus infection. This effect was studied in vitro during lepidopteran-specific nucleopolyhedrovirus (genus Alphabaculovirus, family ...
    • Systematic production of inactivating and non-inactivating suppressor mutations at the relA locus that compensate the detrimental effects of complete spoT loss and affect glycogen content in Escherichia coli 

      Montero Macarro, Manuel Upna; Rahimpour, Mehdi; Viale, Alejandro M. Upna; Almagro Zabalza, Goizeder Upna; Eydallin, Gustavo Upna; Sevilla, Ángel; Cánovas, Manuel; Bernal, Cristina; Lozano, Ana Belén; Muñoz Pérez, Francisco José; Baroja Fernández, Edurne Upna; Bahaji, Abdellatif; Mori, Hirotada; Codoñer, Francisco M.; Pozueta Romero, Javier Upna (Public Library of Science, 2014)   Artículo / Artikulua  OpenAccess
      In Escherichia coli, ppGpp is a major determinant of growth and glycogen accumulation. Levels of this signaling nucleotide are controlled by the balanced activities of the ppGpp RelA synthetase and the dual-function ...
    • Tobacco plastidial thioredoxins as modulators of recombinant protein production in transgenic chloroplasts 

      Sanz Barrio, Ruth; Fernández San Millán, Alicia Upna; Corral-Martínez, Patricia; Seguí-Simarro, José M.; Farrán Blanch, Inmaculada Upna (Wiley, 2011)   Artículo / Artikulua  OpenAccess
      Thioredoxins (Trxs) are small ubiquitous disulphide proteins widely known to enhance expression and solubility of recombinant proteins in microbial expression systems. Given the common evolutionary heritage of chloroplasts ...
    • Towards the identification of the common features of bacterial biofilm development 

      Lasa Uzcudun, Íñigo Upna (Sociedad Española de Microbiología, 2006)   Artículo / Artikulua  OpenAccess
      Los microorganismos pueden vivir y proliferar como células individuales que nadan libremente en el medio o crecer en comunidades multicelulares muy bien organizadas dentro de una matriz que ellas mismas han sintetizado y ...