• Non-systemic fungal endophytes in Carex brevicollis may influence the toxicity of the sedge to livestock 

      Canals Tresserras, Rosa María Upna; San Emeterio Garciandía, Leticia Upna; Sánchez Márquez, Salud; Ruiz de los Mozos Aliaga, Igor Upna; Pujol, Pablo; Zabalgogeazcoa, I. (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)   Artículo / Artikulua  OpenAccess
      The sedge Carex brevicollis is a common component of semi-natural grasslands and forests in temperate mountains of Central and Southern Europe. The consumption of this species causes a severe toxicity to livestock, ...
    • Nontypable haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates 

      Martí Lliteras, Pau; López Gómez, Antonio Upna; Mauro, Silvia; Hood, Derek W.; Viadas Martínez, Cristina Upna; Calatayud, Laura; Morey Sancho, Pau; Servin, Alain; Liñares, Josefina; Oliver, Antonio; Bengoechea Alonso, José Antonio; Garmendia, Junkal (Public Library of Science, 2011)   Artículo / Artikulua  OpenAccess
      Non-typable Haemophilus influenzae (NTHi) is a Gram negative pathogen that causes acute respiratory infections and is associated with the progression of chronic respiratory diseases. Previous studies have established the ...
    • Overlapping transcription and bacterial RNA removal 

      Lasa Uzcudun, Íñigo Upna; Villanueva San Martín, Maite Upna (National Academy of Sciences, 2014)   Artículo / Artikulua  OpenAccess
      The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput ...
    • Post-entry blockade of small ruminant lentiviruses by wild ruminants 

      Sanjosé, Leticia; Crespo, Helena Upna; Blatti-Cardinaux, Laure; Glaría Ezquer, Idoia Upna; Martínez Carrasco, Carlos; Berriatua, Eduardo; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna; Bertoni, Giuseppe; Reina Arias, Ramsés Upna (BioMed Central, 2016)   Artículo / Artikulua  OpenAccess
      Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
    • Post-harvest light treatment increases expression levels of recombinant proteins in transformed plastids of potato tubers 

      Larraya Reta, Luis María Upna; Fernández San Millán, Alicia Upna; Ancín Rípodas, María Upna; Farrán Blanch, Inmaculada Upna; Veramendi Charola, Jon Upna (Wiley, 2015)   Artículo / Artikulua  OpenAccess
      Plastid genetic engineering represents an attractive system for the production of foreign proteins in plants. Although high expression levels can be achieved in leaf chloroplasts, the results for non-photosynthetic plastids ...
    • RinA controls phage-mediated packaging and transfer of virulence genes in gram-positive bacteria 

      Ferrer, María Desamparados; Quiles Puchalt, Nuria; Harwich, Michael D.; Tormo Más, María Ángeles; Campoy Sánchez, Susana; Barbé, Jordi; Lasa Uzcudun, Íñigo Upna; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Oxford University Press, 2011)   Artículo / Artikulua  OpenAccess
      Phage-mediated transfer of microbial genetic elements plays a crucial role in bacterial life style and evolution. In this study, we identify the RinA family of phage-encoded proteins as activators required for transcription ...
    • Salmonella biofilm development depends on the phosphorylation status of RcsB 

      Latasa Osta, Cristina Upna; García Martínez, Begoña Upna; Echeverz Sarasúa, Maite Upna; Toledo Arana, Alejandro Upna; Valle Turrillas, Jaione Upna; Campoy Sánchez, Susana; García del Portillo, Francisco; Solano Goñi, Cristina Upna; Lasa Uzcudun, Íñigo Upna (American Society for Microbiology, 2012)   Artículo / Artikulua  OpenAccess
      The Rcs phosphorelay pathway is a complex signaling pathway involved in the regulation of many cell surface structures in enteric bacteria. In response to environmental stimuli, the sensor histidine kinase (RcsC) ...
    • Simultaneous infections by different Salmonella strains in mesenteric lymph nodes of finishing pigs 

      Garrido, Victoria Upna; Sánchez, Samanta; San Román Aberasturi, Beatriz Upna; Zabalza Baranguá, Ana Upna; Díaz Tendero, Yasmín; Frutos, Cristina de; Mainar Jaime, Raúl Carlos; Grilló Dolset, María Jesús (BioMed Central, 2014)   Artículo / Artikulua  OpenAccess
      Background: Salmonellosis is a major worldwide zoonosis, and Salmonella-infected finishing pigs are considered one of the major sources of human infections in developed countries. Baseline studies on salmonellosis ...
    • Small ruminant lentiviruses: genetic variability, tropism and diagnosis 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna; Martínez, Humberto A. (MDPI, 2013)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV) cause a multisystemic chronic disease affecting animal production and welfare. SRLV infections are spread across the world with the exception of Iceland. Success in controlling SRLV spread ...
    • Small ruminant macrophage polarization may play a pivotal role on lentiviral infection 

      Crespo, Helena Upna; Bertolotti, Luigi; Juganaru, Magda; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna; Amorena Zabalza, Beatriz Upna; Rosati, Sergio; Reina Arias, Ramsés Upna (BioMed Central, 2013)   Artículo / Artikulua  OpenAccess
      Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
    • Spatial distribution and risk factors of brucellosis in Iberian wild ungulates 

      Muñoz Álvaro, Pilar María; Boadella, Mariana; Arnal, Maricruz; Miguel, María Jesús de; Revilla, Miguel; Martínez, David; Vicente, Joaquín; Acevedo, Pelayo; Oleaga, Álvaro; Ruiz Fons, Francisco; Marín, Clara M.; Prieto, José M.; Fuente, José de la; Barral, Marta; Barberán, Montserrat; Fernández de Luco, Daniel; Blasco, José María Upna; Gortázar, Christian (BioMed Central, 2010)   Artículo / Artikulua  OpenAccess
      Background: The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribution ...
    • Staphylococcal Bap proteins build amyloid scaffold biofilm matrices in response to environmental signals 

      Taglialegna, Agustina Upna; Navarro, Susanna; Ventura, Salvador; Garnett, James A.; Matthews, Steve; Penadés, José R.; Lasa Uzcudun, Íñigo Upna; Valle Turrillas, Jaione Upna (Public Library of Science, 2016)   Artículo / Artikulua  OpenAccess
      Major components of the biofilm matrix scaffold are proteins that assemble to create a unified structure that maintain bacteria attached to each other and to surfaces. We provide evidence that a surface protein present in ...
    • Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep 

      Ramírez, Hugo Upna; Reina Arias, Ramsés Upna; Bertolotti, Luigi; Cenoz, Amaia Upna; Hernández, Mirna Margarita; San Román Aberasturi, Beatriz Upna; Glaría Ezquer, Idoia Upna; Andrés, Ximena de; Crespo, Helena Upna; Jauregui, Paula; Benavides, Julio; Polledo, Laura; Pérez, Valentín; García Marín, Juan F.; Rosati, Sergio; Amorena Zabalza, Beatriz Upna; Andrés Cara, Damián de Upna (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
    • Towards the identification of the common features of bacterial biofilm development 

      Lasa Uzcudun, Íñigo Upna (Sociedad Española de Microbiología, 2006)   Artículo / Artikulua  OpenAccess
      Los microorganismos pueden vivir y proliferar como células individuales que nadan libremente en el medio o crecer en comunidades multicelulares muy bien organizadas dentro de una matriz que ellas mismas han sintetizado y ...
    • The Vip3Ag4 insecticidal protoxin from bacillus thuringiensis adopts a tetrameric configuration that is maintained on proteolysis 

      Palma Dovis, Leopoldo Upna; Scott, David J.; Harris, Gemma; Din, Salah-Ud; Williams, Thomas L.; Roberts, Oliver J.; Young, Mark T.; Caballero Murillo, Primitivo Upna; Berry, Colin (MDPI, 2017)   Artículo / Artikulua  OpenAccess
      The Vip3 proteins produced during vegetative growth by strains of the bacterium Bacillus thuringiensis show insecticidal activity against lepidopteran insects with a mechanism of action that may involve pore formation and ...
    • Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray 

      Segura, Víctor; Toledo Arana, Alejandro Upna; Uzqueda, Maite; Lasa Uzcudun, Íñigo Upna; Muñoz Barrutia, Arrate (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Background: High-density oligonucleotide microarray is an appropriate technology for genomic analysis, and is particulary useful in the generation of transcriptional maps, ChIP-on-chip studies and re-sequencing of the ...
    • What have we learned from brucellosis in the mouse model? 

      Grilló Dolset, María Jesús; Blasco, José María Upna; Gorvel, Jean-Pierre; Moriyón Uría, Ignacio; Moreno, Edgardo (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...