• Lacanobia oleracea nucleopolyhedrovirus (LaolNPV): a new European species of alphabaculovirus with a narrow host range 

      Simón de Goñi, Oihane Upna Orcid; Erlandson, Martin A.; Frayssinet, Marie; Williams, Trevor Upna; Theilmann, David A.; Volkoff, Anne Nathalie; Caballero Murillo, Primitivo Upna Orcid (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      During an insect sampling program in alfalfa crops near Montpellier, France in 2011, Lacanobia oleracea larvae were collected that died due to nucleopolyhedrovirus infection (LaolNPV). This virus was subjected to molecular ...
    • Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers 

      Salazar, Eider; Berriatua, Eduardo; Pérez, Marta María; Marín, Belén; Acín, Cristina; Martín Burriel, Inmaculada; Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria (INIA), 2014)   Artículo / Artikulua  OpenAccess
      The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and ...
    • Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host 

      Echeverz Sarasúa, Maite Upna Orcid; García Martínez, Begoña Upna Orcid; Sabalza Baztán, Amaia Upna; Valle Turrillas, Jaione Upna Orcid; Gabaldón Estevan, Juan Antonio; Solano Goñi, Cristina Upna Orcid; Lasa Uzcudun, Íñigo Upna Orcid (Public Library of Science, 2017)   Artículo / Artikulua  OpenAccess
      Many bacteria build biofilm matrices using a conserved exopolysaccharide named PGA or PNAG (poly-β-1,6-N-acetyl-D-glucosamine). Interestingly, while E. coli and other members of the family Enterobacteriaceae encode the ...
    • Leaf δ15N as a physiological indicator of the responsiveness of N2-fixing alfalfa plants to elevated CO2, temperature and low water availability 

      Ariz, Idoia Upna Orcid; Cruz, Cristina; Neves, Tomé; Irigoyen, Juan J.; García Olaverri, Carmen Upna Orcid; Nogués, Salvador; Aparicio Tejo, Pedro María Upna Orcid; Aranjuelo Michelena, Iker Upna Orcid (Frontiers Media, 2015)   Artículo / Artikulua  OpenAccess
      The natural 15N/14N isotope composition (δ15N) of a tissue is a consequence of its N source and N physiological mechanisms in response to the environment. It could potentially be used as a tracer of N metabolism in plants ...
    • Lentinula edodes β-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit 

      Crespo, Helena Upna; Guillén, Hugo; Pablo Maiso, Lorena de Upna Orcid; Gómez Arrebola, Carmen Upna Orcid; Rodríguez, Gregorio; Glaría Ezquer, Idoia Upna; Andrés Cara, Damián de Upna Orcid; Reina Arias, Ramsés Upna Orcid (Taylor & Francis, 2017)   Artículo / Artikulua  OpenAccess
      β-glucans exhibited in cell walls of several pathogens as bacteria or fungi are sensed by pathogen recognition receptors such as scavenger receptors present in antigen presenting cells, i.e., macrophages. β-glucans obtained ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero-Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012)   Artículo / Artikulua  OpenAccess
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • Maedi-visna virus infection of ovine mammary epithelial cells 

      Bolea, Rosa; Monleón, Eva; Carrasco, Librado; Vargas, Antonia; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Badiola, Juan José; Luján, Lluís (EDP Sciences, 2006)   Artículo / Artikulua  OpenAccess
      The aim of this work was to perform a complete study of maedi-visna virus (MVV) infected mammary glands of naturally-infected sheep, and to determine if cells other than macrophages undergo a productive viral infection in ...
    • Mannose receptor may be involved in small ruminant lentivirus pathogenesis 

      Crespo, Helena Upna; Jauregui, Paula; Glaría Ezquer, Idoia Upna; Sanjosé, Leticia; Polledo, Laura; García Marín, Juan F.; Luján, Lluís; Andrés Cara, Damián de Upna Orcid; Amorena Zabalza, Beatriz Upna; Reina Arias, Ramsés Upna Orcid (BioMed Central, 2012)   Artículo / Artikulua  OpenAccess
      Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
    • Mechanisms of ammonium toxicity and the quest for tolerance 

      Esteban Terradillos, Raquel; Ariz, Idoia Upna Orcid; Cruz, Cristina; Morán Juez, José Fernando Upna Orcid (Elsevier, 2016)   Artículo / Artikulua  OpenAccess
      Ammonium sensitivity of plants is a worldwide problem, constraining crop production. Prolonged application of ammonium as the sole nitrogen source may result in physiological and morphological disorders that lead to decreased ...
    • Mixtures of complete and pif1- and pif2-deficient genotypes are required for increased potency of an insect nucleopolyhedrovirus 

      Clavijo Palacios, Gabriel Upna; Williams, Trevor Upna; Simón de Goñi, Oihane Upna Orcid; Muñoz Labiano, Delia Upna Orcid; Cerutti, Martine; López Ferber, Miguel; Caballero Murillo, Primitivo Upna Orcid (American Society for Microbiology, 2009)   Artículo / Artikulua  OpenAccess
      The insecticidal potency of a nucleopolyhedrovirus population (SfNIC) that infects Spodoptera frugiperda (Lepidoptera) is greater than the potency of any of the component genotypes alone. Occlusion bodies (OBs) produced ...
    • Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella 

      Insua, José Luis; Llobet, Enrique; Moranta, David; Pérez Gutiérrez, Camino; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Microbiology, 2013)   Artículo / Artikulua  OpenAccess
      The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ...
    • Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways 

      Fernández Calvet, Ariadna Upna; Rodríguez Arce, Irene Upna; Almagro Zabalza, Goizeder Upna Orcid; Moleres Apilluelo, Javier Upna Orcid; Caballero Coronado, Lucía; Garmendia García, Juncal (Springer, 2018)   Artículo / Artikulua  OpenAccess
      Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in ...
    • Molecular and insecticidal characterization of a novel cry-related protein from bacillus thuringiensis toxic against Myzus persicae 

      Palma Dovis, Leopoldo Upna Orcid; Muñoz Labiano, Delia Upna Orcid; Berry, Colin; Murillo Martínez, Jesús Upna Orcid; Escudero, Iñigo de; Caballero Murillo, Primitivo Upna Orcid (MDPI, 2014)   Artículo / Artikulua  OpenAccess
      This study describes the insecticidal activity of a novel Bacillus thuringiensis Cry-related protein with a deduced 799 amino acid sequence (~89 kDa) and ~19% pairwise identity to the 95-kDa-aphidicidal protein (sequence ...
    • Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing 

      Varela Martínez, Endika; Abendaño, Naiara; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta María; Reina Arias, Ramsés Upna Orcid; Andrés Cara, Damián de Upna Orcid; Luján, Lluís; Jugo, Begoña M. (Frontiers Media, 2018)   Artículo / Artikulua  OpenAccess
      There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...
    • Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands 

      Tormo Más, María Ángeles; Mir, Ignacio; Shrestha, Archana; Tallent, Sandra M.; Campoy Sánchez, Susana; Lasa Uzcudun, Íñigo Upna Orcid; Barbé, Jordi; Novick, Richard P.; Christie, Gail E.; Penadés, José R. (Nature Research, 2010)   Artículo / Artikulua  OpenAccess
      Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete, chromosomally integrated units of ∼15 kilobases that are induced by helper phages to excise and replicate. SaPI DNA is then efficiently ...
    • Most of ADP-glucose linked to starch biosynthesis occurs outside the chloroplast in source leaves 

      Baroja Fernández, Edurne Upna Orcid; Muñoz Pérez, Francisco José Upna; Zandueta Criado, Aitor Upna; Morán Zorzano, María Teresa Upna; Viale, Alejandro M. Upna; Alonso Casajús, Nora Upna; Pozueta Romero, Javier Upna Orcid (National Academy of Sciences, 2004)   Artículo / Artikulua  OpenAccess
      Sucrose and starch are end products of two segregated gluconeogenic pathways, and their production takes place in the cytosol and chloroplast of green leaves, respectively. According to this view, the plastidial ADP ...
    • Multidrug resistant Salmonella enterica isolated from conventional pig farms using antimicrobial agents in preventative medicine programmes 

      Cameron Veasa, Karla; Fraile, Lorenzo; Nappa, Sebastian; Garrido, Victoria Upna; Grilló Dolset, María Jesús (Elsevier, 2018)   Artículo / Artikulua  OpenAccess
      A longitudinal study was conducted to investigate the presence of multidrug antimicrobial resistance (multi-AR) in Salmonella enterica in pigs reared under conventional preventative medicine programmes in Spain and the ...
    • Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice 

      Soler Lloréns, Pedro; Gil Ramírez, Yolanda Upna; Zabalza Baranguá, Ana Upna; Iriarte, Maite; Conde Álvarez, Raquel; Zúñiga Ripa, Amaia; San Román Aberasturi, Beatriz Upna Orcid; Zygmunt, Michel; Vizcaíno, Nieves; Cloeckaert, Axel; Grilló Dolset, María Jesús; Moriyón Uría, Ignacio; López Goñi, Ignacio (BioMed Central, 2014)   Artículo / Artikulua  OpenAccess
      Brucella spp. are Gram-negative bacteria that behave as facultative intracellular parasites of a variety of mammals. This genus includes smooth (S) and rough (R) species that carry S and R lipopolysaccharides (LPS), ...
    • N-glycomic and microscopic subcellular localization analyses of NPP1, 2 and 6 strongly indicate that trans-Golgi compartments participate in the Golgi to plastid traffic of nucleotide pyrophosphatase/phosphodiesterases in rice 

      Kaneko, Kentaro; Takamatsu, Takeshi; Inomata, Takuya; Oikawa, Kazusato; Pozueta Romero, Javier Upna Orcid (Oxford University Press, 2016)   Artículo / Artikulua  OpenAccess
      Nucleotide pyrophosphatase/phosphodiesterases (NPPs) are widely distributed N-glycosylated enzymes that catalyze the hydrolytic breakdown of numerous nucleotides and nucleotide sugars. In many plant species, NPPs are encoded ...
    • Near-infrared fluorescence imaging as an alternative to bioluminescent bacteria to monitor biomaterial-associated infections 

      Dinjaski, Nina; Shalu, Suri; Valle Turrillas, Jaione Upna Orcid; Lehman, Susan M.; Lasa Uzcudun, Íñigo Upna Orcid; Prieto, María Auxiliadora; García, Andrés J. (Elsevier, 2014)   Artículo / Artikulua  OpenAccess
      Biomaterial-associated infection is one of the most common complications related with the implantation of any biomedical device. Several in vivo imaging platforms have emerged as powerful diagnostic tools to longitudinally ...

      El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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