Listar Artículos de revista IdAB - IdAB Aldizkari artikuluak por autor "Bengoechea Alonso, José Antonio"
Mostrando ítems 1-12 de 12
-
Apoptosis, toll-like, RIG-I-like and NOD-like receptors are pathways jointly induced by diverse respiratory bacterial and viral pathogens
Martínez, Isidoro; Oliveros, Juan C.; Cuesta, Isabel; Barrera, Jorge de la; Ausina, Vicente; Casals, Cristina; Lorenzo, Alba de; García, Ernesto; García Fojeda, Belén; Garmendia García, Juncal; González Nicolau, Mar; Lacoma, Alicia; Menéndez, Margarita; Moranta, David; Nieto, Amelia; Ortín, Juan; Pérez González, Alicia; Prat, Cristina; Ramos Sevillano, Elisa; Regueiro, Verónica; Rodríguez Frandsen, Ariel; Solís, Dolores; Yuste, José E.; Bengoechea Alonso, José Antonio; Melero, José A. (Frontiers Media, 2017) Artículo / ArtikuluaLower respiratory tract infections are among the top five leading causes of human death. Fighting these infections is therefore a world health priority. Searching for induced alterations in host gene expression shared by ... -
Characterization of nontypable haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection
Garmendia García, Juncal; Viadas Martínez, Cristina ; Calatayud, Laura; Mell, Joshua Chang; Martí Lliteras, Pau; Euba, Begoña; Llobet, Enrique; Gil Puig, Carmen ; Bengoechea Alonso, José Antonio; Redfield, Rosemary J.; Liñares, Josefina (Public Library of Science, 2014) Artículo / ArtikuluaNontypable Haemophilus influenzae (NTHi) has emerged as an important opportunistic pathogen causing infection in adults suffering obstructive lung diseases. Existing evidence associates chronic infection by NTHi to the ... -
Genome expression profiling-based identification and administration efficacy of host-directed antimicrobial drugs against respiratory infection by nontypeable Haemophilus influenzae
Euba, Begoña; Moleres Apilluelo, Javier ; Segura, Víctor; Viadas Martínez, Cristina ; Morey Sancho, Pau; Moranta, David; Leiva, José; Torres, Juan de; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2015) Artículo / ArtikuluaTherapies that are safe, effective, and not vulnerable to developing resistance are highly desirable to counteract bacterial infections. Host-directed therapeutics is an antimicrobial approach alternative to conventional ... -
Identification of lptA, lpxE, and lpxO, three genes involved in the remodeling of Brucella cell envelope
Conde Álvarez, Raquel; Palacios Chaves, Leyre; Gil Ramírez, Yolanda ; Salvador Bescós, Miriam; Bárcena-Varela, Marina; Aragón Aranda, Beatriz; Martínez Gómez, Estrella; Zúñiga Ripa, Amaia; Miguel López, María Jesús de; Bartholomew, Toby Leigh; Hanniffy, Sean; Grilló Dolset, María Jesús; Vences Guzmán, Miguel Ángel; Bengoechea Alonso, José Antonio; Arce Gorvel, Vilma; Gorvel, Jean-Pierre; Moriyón Uría, Ignacio; Iriarte, Maite (Frontiers Media, 2018) Artículo / ArtikuluaThe brucellae are facultative intracellular bacteria that cause a worldwide extended zoonosis. One of the pathogenicity mechanisms of these bacteria is their ability to avoid rapid recognition by innate immunity because ... -
Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells
March, Catalina; Moranta, David; Regueiro, Verónica; Llobet, Enrique; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Biochemistry and Molecular Biology, 2011) Artículo / ArtikuluaOuter membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated Gram-negative pathogen. It is an important cause ... -
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
Conde Álvarez, Raquel; Bargen, Kristine von; Grilló Dolset, María Jesús; Jerala, Roman; Brandenburg, Klaus; Llobet, Enrique; Bengoechea Alonso, José Antonio; Moreno, Edgardo; Moriyón Uría, Ignacio; Gorvel, Jean-Pierre; Arce Gorvel, Vilma; Iriarte, Maite; Mancek Keber, Mateja; Barquero-Calvo, Elías; Palacios Chaves, Leyre; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Martirosyan, Anna (Public Library of Science, 2012) Artículo / ArtikuluaInnate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ... -
Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella
Insua, José Luis; Llobet, Enrique; Moranta, David; Pérez Gutiérrez, Camino; Tomás, Anna; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (American Society for Microbiology, 2013) Artículo / ArtikuluaThe implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ... -
Nontypable haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates
Martí Lliteras, Pau; López Gómez, Antonio ; Mauro, Silvia; Hood, Derek W.; Viadas Martínez, Cristina ; Calatayud, Laura; Morey Sancho, Pau; Servin, Alain; Liñares, Josefina; Oliver, Antonio; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (Public Library of Science, 2011) Artículo / ArtikuluaNon-typable Haemophilus influenzae (NTHi) is a Gram negative pathogen that causes acute respiratory infections and is associated with the progression of chronic respiratory diseases. Previous studies have established the ... -
Relationship between azithromycin susceptibility and administration efficacy for nontypeable Haemophilus influenzae respiratory infection
Euba, Begoña; Moleres Apilluelo, Javier ; Viadas Martínez, Cristina ; Barberán, Montserrat; Caballero Coronado, Lucía; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Torres, Juan de; Liñares, Josefina; Leiva, José; Garmendia García, Juncal (American Society for Microbiology, 2015) Artículo / ArtikuluaNontypeable Haemophilus influenzae (NTHI) is an opportunistic pathogen that is an important cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). COPD is an inflammatory disease of the airways, ... -
Relative contribution of P5 and hap surface proteins to nontypable haemophilus influenzae interplay with the host upper and lower airways
Euba, Begoña; Moleres Apilluelo, Javier ; Viadas Martínez, Cristina ; Ruiz de los Mozos Aliaga, Igor ; Valle Turrillas, Jaione ; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (Public Library of Science, 2015) Artículo / ArtikuluaNontypable Haemophilus influenzae (NTHi) is a major cause of opportunistic respiratory tract disease, and initiates infection by colonizing the nasopharynx. Bacterial surface proteins play determining roles in the ... -
Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis
Morey, Pau; Viadas Martínez, Cristina ; Euba, Begoña; Hood, Derek W.; Barberán, Montserrat; Gil Puig, Carmen ; Grilló Dolset, María Jesús; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2013) Artículo / ArtikuluaNontypeable Haemophilus influenzae (NTHi) is a frequent commensal of the human nasopharynx that causes opportunistic infection in immunocompromised individuals. Existing evidence associates lipooligosaccharide (LOS) with ... -
Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
March, Catalina; Cano, Victoria; Moranta, David; Llobet, Enrique; Pérez Gutiérrez, Camino; Tomás, Juan M.; Suárez, Teresa; Garmendia García, Juncal; Bengoechea Alonso, José Antonio (Public Library of Science, 2013) Artículo / ArtikuluaPhagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...