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Study of compartmentalization in the visna clinical form of small ruminant lentivirus infection in sheep
(BioMed Central, 2012)
Artículo / Artikulua,
Background: A central nervous system (CNS) disease outbreak caused by small ruminant lentiviruses (SRLV) has triggered interest in Spain due to the rapid onset of clinical signs and relevant production losses. In a previous ...
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection
(BioMed Central, 2011)
info:eu-repo/semantics/article,
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having ...
Mannose receptor may be involved in small ruminant lentivirus pathogenesis
(BioMed Central, 2012)
info:eu-repo/semantics/article,
Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose receptor (MR) ...
Small ruminant macrophage polarization may play a pivotal role on lentiviral infection
(BioMed Central, 2013)
info:eu-repo/semantics/article,
Small ruminant lentiviruses (SRLV) infect the monocyte/macrophage lineage inducing a long-lasting infection affecting body condition, production and welfare of sheep and goats all over the world. Macrophages play a pivotal ...
Ovine TRIM5α can restrict visna/maedi virus
(American Society for Microbiology, 2012)
info:eu-repo/semantics/article,
The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored.
Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ...
Molecular signature of aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing
(Frontiers Media, 2018)
info:eu-repo/semantics/article,
There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...
Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq
(BioMed Central, 2019)
info:eu-repo/semantics/article,
Background: MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, ...
The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice
(BioMed Central, 2012)
Artículo / Artikulua,
The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigated the adjuvant ...
Post-entry blockade of small ruminant lentiviruses by wild ruminants
(BioMed Central, 2016)
Artículo / Artikulua,
Small ruminant lentivirus (SRLV) infection causes losses in the small ruminant industry due to reduced animal production
and increased replacement rates. Infection of wild ruminants in close contact with infected domestic ...
Extensive rearing hinders Maedi-Visna Virus (MVV) infection in sheep
(EDP Sciences, 2006)
info:eu-repo/semantics/article,
Maedi-Visna Virus (MVV) seroprevalence and its relationship with housing and mode
of rearing of replacement ewe-lambs was investigated in 38 non-randomly selected sheep-flocks in
Spain. They included extensive lamb-producing ...