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Nontypable haemophilus influenzae displays a prevalent surface structure molecular pattern in clinical isolates
(Public Library of Science, 2011)
Artículo / Artikulua,
Non-typable Haemophilus influenzae (NTHi) is a Gram negative pathogen that causes acute respiratory infections and is associated with the progression of chronic respiratory diseases. Previous studies have established the ...
Inactivation of the Thymidylate synthase thyA in non-typeable Haemophilus influenzae modulates antibiotic resistance and has a strong impact on its interplay with the host airways
(Frontiers Media, 2017)
info:eu-repo/semantics/article,
Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate ...
Apoptosis, toll-like, RIG-I-like and NOD-like receptors are pathways jointly induced by diverse respiratory bacterial and viral pathogens
(Frontiers Media, 2017)
info:eu-repo/semantics/article,
Lower respiratory tract infections are among the top five leading causes of human death. Fighting these infections is therefore a world health priority. Searching for induced alterations in host gene expression shared by ...
Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella
(American Society for Microbiology, 2013)
info:eu-repo/semantics/article,
The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ...
Deciphering tissue-induced Klebsiella pneumoniae lipid A structure
(National Academy of Sciences, 2015)
info:eu-repo/semantics/article,
The outcome of an infection depends on host recognition of the
pathogen, hence leading to the activation of signaling pathways
controlling defense responses. A long-held belief is that the modification
of the lipid A ...
Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells
(American Society for Biochemistry and Molecular Biology, 2011)
info:eu-repo/semantics/article,
Outer membrane protein A (OmpA) is a class of proteins
highly conserved among the Enterobacteriaceae family and
throughout evolution. Klebsiella pneumoniae is a capsulated
Gram-negative pathogen. It is an important cause ...
Novel blaROB-1-bearing plasmid conferring resistance to β-lactams in Haemophilus parasuis isolates from healthy weaning pigs
(American Society for Microbiology, 2015)
info:eu-repo/semantics/article,
Haemophilus parasuis, the causative agent of Glässer’s disease, is one of the early colonizers of the nasal mucosa of piglets. It is
prevalent in swine herds, and lesions associated with disease are fibrinous polyserositis ...
Characterization of nontypable haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection
(Public Library of Science, 2014)
info:eu-repo/semantics/article,
Nontypable Haemophilus influenzae (NTHi) has emerged as an important opportunistic pathogen causing infection in adults
suffering obstructive lung diseases. Existing evidence associates chronic infection by NTHi to the ...
Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
(Public Library of Science, 2013)
info:eu-repo/semantics/article,
Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example
of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...
Relative contribution of P5 and hap surface proteins to nontypable haemophilus influenzae interplay with the host upper and lower airways
(Public Library of Science, 2015)
info:eu-repo/semantics/article,
Nontypable Haemophilus influenzae (NTHi) is a major cause of opportunistic respiratory
tract disease, and initiates infection by colonizing the nasopharynx. Bacterial surface proteins
play determining roles in the ...