Biofilm dispersion and quorum sensing
Fecha
2014Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión aceptada / Onetsi den bertsioa
Impacto
|
10.1016/j.mib.2014.02.008
Resumen
Biofilm development and quorum sensing are closely interconnected processes. Biofilm
formation is a cooperative group behaviour that involves bacterial populations living
embedded in a self produced extracellular matrix. Quorum sensing (QS) is a cell-cell
communication mechanism that synchronizes gene expression in response to population
cell density. Intuitively, it would appear that QS migh ...
[++]
Biofilm development and quorum sensing are closely interconnected processes. Biofilm
formation is a cooperative group behaviour that involves bacterial populations living
embedded in a self produced extracellular matrix. Quorum sensing (QS) is a cell-cell
communication mechanism that synchronizes gene expression in response to population
cell density. Intuitively, it would appear that QS might coordinate the switch to a
biofilm lifestyle when the population density reaches a threshold level. However,
compelling evidence obtained in different bacterial species coincides in that activation
of QS occurs in the formed biofilm and activates the maturation and disassembly of the
biofilm in a coordinate manner. The aim of this review is to illustrate, using four
bacterial pathogens as examples, the emergent concept that QS activates the biofilm
dispersion process. [--]
Materias
Biofilm dispersion,
Quorum sensing
Editor
Elsevier
Publicado en
Current Opinion in Microbiology 2014, 18:96–104
Departamento
Universidad Pública de Navarra/Nafarroako Unibertsitate Publikoa. IdAB. Instituto de Agrobiotecnología / Agrobioteknologiako Institutua
Versión del editor
Entidades Financiadoras
Work in the Laboratory of Microbial Biofilms is funded by the Spanish Ministry of Economy and Competitiveness grants BIO2011-30503-C02-02, as well as ERA-NET Pathogenomics (PIM2010EPA-00606) and grant from the Departamento de Innovación (IIM13329.RI1), Gobierno de Navarra.