Show simple item record

dc.creatorReina Arias, Ramséses_ES
dc.creatorAndrés Cara, Damián dees_ES
dc.creatorAmorena Zabalza, Beatrizes_ES
dc.date.accessioned2017-11-15T08:00:42Z
dc.date.available2017-11-15T08:00:42Z
dc.date.issued2013
dc.identifier.issn1999-4915
dc.identifier.urihttps://hdl.handle.net/2454/26137
dc.description.abstractMultisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare. This, together with the lack of treatments, has triggered interest in exploring different strategies of immunization to control the widely spread SRLV infection and, also, to provide a useful model for HIV vaccines. These strategies involve inactivated whole virus, subunit vaccines, DNA encoding viral proteins in the presence or absence of plasmids encoding immunological adjuvants and naturally or artificially attenuated viruses. In this review, we revisit, comprehensively, the immunization strategies against SRLV and analyze this double edged tool individually, as it may contribute to either controlling or enhancing virus replication and/or disease.en
dc.description.sponsorshipFunded by CICYT (AGL2010-22341-C04-01) and Gobierno de Navarra (IIQ14064.RI1). RR was funded by a CSIC JAE-Doc contract.en
dc.format.extent16 p.
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.relation.ispartofViruses, 5(8), 1948-1963en
dc.rights© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.en
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/
dc.subjectSmall ruminant lentivirusen
dc.subjectMaedi-Visnaen
dc.subjectImmunizationen
dc.titleImmunization against small ruminant lentivirusesen
dc.typeArtículo / Artikuluaes
dc.typeinfo:eu-repo/semantics/articleen
dc.contributor.departmentIdAB - Instituto de Agrobiotecnología / Agrobioteknologiako Institutuaes
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.identifier.doi10.3390/v5081948
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/6PN/AGL2010-22341en
dc.relation.publisherversionhttps://dx.doi.org/10.3390/v5081948
dc.type.versionVersión publicada / Argitaratu den bertsioaes
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.contributor.funderGobierno de Navarra / Nafarroako Gobernua: IIQ14064.RI1es


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article
distributed under the terms and conditions of the Creative Commons Attribution license.
Except where otherwise noted, this item's license is described as © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.