Show simple item record

dc.creatorPalma Dovis, Leopoldoes_ES
dc.creatorMuñoz, Deliaes_ES
dc.creatorBerry, Colines_ES
dc.creatorMurillo Martínez, Jesúses_ES
dc.creatorCaballero Murillo, Primitivoes_ES
dc.date.accessioned2017-11-15T09:28:39Z
dc.date.available2017-11-15T09:28:39Z
dc.date.issued2014
dc.identifier.issn2072-6651
dc.identifier.urihttps://hdl.handle.net/2454/26161
dc.description.abstractBacillus thuringiensis (Bt) is a Gram positive, spore-forming bacterium that synthesizes parasporal crystalline inclusions containing Cry and Cyt proteins, some of which are toxic against a wide range of insect orders, nematodes and human-cancer cells. These toxins have been successfully used as bioinsecticides against caterpillars, beetles, and flies, including mosquitoes and blackflies. Bt also synthesizes insecticidal proteins during the vegetative growth phase, which are subsequently secreted into the growth medium. These proteins are commonly known as vegetative insecticidal proteins (Vips) and hold insecticidal activity against lepidopteran, coleopteran and some homopteran pests. A less well characterized secretory protein with no amino acid similarity to Vip proteins has shown insecticidal activity against coleopteran pests and is termed Sip (secreted insecticidal protein). Bin-like and ETX_MTX2-family proteins (Pfam PF03318), which share amino acid similarities with mosquitocidal binary (Bin) and Mtx2 toxins, respectively, from Lysinibacillus sphaericus, are also produced by some Bt strains. In addition, vast numbers of Bt isolates naturally present in the soil and the phylloplane also synthesize crystal proteins whose biological activity is still unknown. In this review, we provide an updated overview of the known active Bt toxins to date and discuss their activities.en
dc.description.sponsorshipThis research was supported by the Spanish Ministry of Science and Innovation (grant reference AGL2009-13340-C02) and by the Universidad Pública de Navarra (PhD contract awarded to Leopoldo Palma).en
dc.format.extent30 p.
dc.format.mimetypeapplication/pdfen
dc.language.isoenen
dc.publisherMDPIen
dc.relation.ispartofToxins, 2014, 6(12), 3296-3325en
dc.rights© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBacillus thuringiensisen
dc.subjectBt biopesticidesen
dc.subjectToxic activityen
dc.subjectCry toxinsen
dc.subjectCyt toxinsen
dc.subjectVip toxinsen
dc.subjectSip toxinsen
dc.subjectParasporinsen
dc.titleBacillus thuringiensis toxins: an overview of their biocidal activityen
dc.typeArtículo / Artikuluaes
dc.typeinfo:eu-repo/semantics/articleen
dc.contributor.departmentUniversidad Pública de Navarra. Departamento de Producción Agrariaes_ES
dc.contributor.departmentNafarroako Unibertsitate Publikoa. Nekazaritza Ekoizpena Sailaeu
dc.contributor.departmentIdAB - Instituto de Agrobiotecnología / Agrobioteknologiako Institutuaes
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.identifier.doi10.3390/toxins6123296
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/6PN/AGL2009-13340en
dc.relation.publisherversionhttps://dx.doi.org/10.3390/toxins6123296
dc.type.versionVersión publicada / Argitaratu den bertsioaes
dc.type.versioninfo:eu-repo/semantics/publishedVersionen


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.
Except where otherwise noted, this item's license is described as © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.