Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults
Acceso abierto / Sarbide irekia
Artículo / Artikulua
Versión publicada / Argitaratu den bertsioa
Background: Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determine the effects of moderate (MCT)- versus high-intensity interval training (HIT) on vascular function param ... [++]
Background: Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases, such as cardiovascular disease (CVD), metabolic syndrome, and breast and colon cancers, and shortens life expectancy. We aimed to determine the effects of moderate (MCT)- versus high-intensity interval training (HIT) on vascular function parameters in physically inactive adults. We hypothesized that individualized HIT prescription would improve the vascular function parameters more than the MCT in a greater proportion of individuals. Methods; Twenty-one inactive adults were randomly allocated to receive either MCT group (60-75% of their heart rate reserve, [HRR] or HIT group (4min at 85-95% of peak HRR), 3 days a week for 12weeks. Vascular function (brachial artery flow-mediated dilation, FMD [%], normalized brachial artery flow-mediated dilation, FMDn [%], aortic pulse wave velocity, PWV [ms(-1)], AIx, augmentation index: aortic and brachial [%]), were measured at baseline and over 12weeks of training. In order for a participant to be considered a responder to improvements in vascular function parameters (FMDn and PWV), the typical error was calculated in a favorable direction. Results: FMD changed by -1.0% (SE 2.1, d=0.388) in the MCT group, and+1.8% (SE 1.8, d=0.699) in the HIT group (no significant difference between groups: 2.9% [95% CI, -3.0 to 8.8]. PWV changed by +0.1ms(-1) (SE 0.2, d=0.087) in the MCT group but decreased by -0.4ms(-1) in the HIT group (SE 0.2, d=0.497), with significant difference between groups: -0.4 [95% CI, -0.2 to -0.7]. There was not a significant difference in the prevalence of no-responder for FMD (%) between the MCT and HIT groups (66% versus 36%, P=0.157). Regarding PWV (ms(-1)), an analysis showed that the prevalence of no-responder was 77% (7 cases) in the MCT group and 45% (5 cases) in the HIT group (P=0.114). Conclusions: Under the conditions of the present study, both groups experienced changed in vascularfunction parameters. Compared to MCT group, HIT is more efficacious for improving FMD and decreasing PWV, in physically inactive adults. [--]
Lipids in Health and Disease, 2019, 18:42
Universidad Pública de Navarra. Departamento de Ciencias de la Salud / Nafarroako Unibertsitate Publikoa. Osasun Zientziak Saila
This study was part of the project entitled 'Body Adiposity Index and Biomarkers of Endothelial and Cardiovascular Health in Adults: Effect of Physical Training', which was funded by Centre for Studies on Measurement of Physical Activity, School of Medicine and Health Sciences, Universidad del Rosario (Code No FIUR DN-BG001).
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