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dc.creatorArenaza, Lidees_ES
dc.creatorMedrano Echeverría, Maríaes_ES
dc.creatorOsés Recalde, Maddies_ES
dc.creatorHuybrechts, Ingees_ES
dc.creatorDíez, Ignacioes_ES
dc.creatorHenriksson, Hannaes_ES
dc.creatorLabayen Goñi, Idoiaes_ES
dc.date.accessioned2020-01-07T12:20:39Z
dc.date.available2020-05-28T23:00:14Z
dc.date.issued2019
dc.identifier.issn7114-1145
dc.identifier.urihttps://hdl.handle.net/2454/35992
dc.description.abstractPediatric non-alcoholic fatty liver disease (NAFLD) has increased in parallel with childhood obesity. Dietary habits, particularly products rich in sugars, may influence both hepatic fat and insulin resistance (HOMA-IR). The aim of the study was to examine the associations of the consumption of foods (cereals, fruits and vegetables, meat/meat products, dairy products, dairy desserts/substitutes (DDS) fish/shellfish, total and added sugars), sugar-sweetened beverages (SSB) and food components (macronutrients and fiber), on hepatic fat and HOMA-IR. Dietary intake (two non-consecutive 24h-recalls), hepatic fat (magnetic resonance imaging) and HOMA-IR were assessed in 110 children (10.6-1.1 years old) with overweight/obesity. Linear regression analyses were used to examine the associations of dietary intake with hepatic fat and HOMA-IR adjusted for potential confounders (sex, age, energy intake, maternal educational level, total and abdominal adiposity and sugar intake). The results showed that there was a negative association between cereal intake and hepatic fat (-0.197, P<0.05). In contrast, both SSB consumption (=0.217; P=0.028) and sugar in SSB (=0.210, P=0.035), but not DDS or sugar in DDS or other dietary components, were positively associated with hepatic fat regardless of potential confounders including total sugar intake. In conclusion, cereal intake might decrease hepatic fat, whereas SSB consumption and its sugar content may increase the likelihood of having hepatic steatosis. Although these observations need to be confirmed using experimental evidence, these results suggest that healthy lifestyle intervention programs are needed to improve dietary habits as well as to increase the awareness of the detrimental effects of SSB consumption early in life.en
dc.description.sponsorshipThis project was supported by the Spanish Ministry of Industry and Competitiveness (DEP2016-78377-R), by ‘Fondos Estructurales de la Unión Europea (FEDER), Una manera de hacer Europa’ and by the University of the Basque Country (GIU14/21). This work was also supported by grants from Spanish Ministry of Economy and Competitiveness (RYC 2010-05957; RYC-2011-09011), by the Education Department of the Government of the Basque Country (PRE_2016_1_0057, PRE_2017_2_0224 and PRE_2018_2_0057), by the Spanish Ministry of Education, Culture and Sports (FPU14/03329), and by the Swedish Society of Medicine.en
dc.format.extent8 p.
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherCambridge University Pressen
dc.relation.ispartofBritish Journal of Nutrition (2019), 121, 1158–1165en
dc.rights© The Authors 2019en
dc.subjectHepatic steatosisen
dc.subjectChildhood obesityen
dc.subjectHomeostatic model assessment for insulin resistanceen
dc.subjectDietary intakeen
dc.subjectSugar-sweetened beveragesen
dc.titleDietary determinants of hepatic fat content and insulin resistance in overweight/obese children: a cross-sectional analysis of the Prevention of Diabetes in Kids (PREDIKID) studyen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeArtículo / Artikuluaes
dc.contributor.departmentUniversidad Pública de Navarra / Nafarroako Unibertsitate Publikoa. ISFOOD - Institute on Innovation & Sustainable Development in Food Chaines_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.embargo.terms2020-05-28
dc.identifier.doi10.1017/S0007114519000436
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/DEP2016-78377-Ren
dc.relation.publisherversionhttps://doi.org/10.1017/S0007114519000436
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.type.versionVersión publicada / Argitaratu den bertsioaes


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