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dc.creatorJiménez Moreno, Nereaes_ES
dc.creatorCimminelli, María Josées_ES
dc.creatorVolpe Sainz, Francescaes_ES
dc.creatorAnsó Blanco, Raúles_ES
dc.creatorEsparza Catalán, Irenees_ES
dc.creatorMármol, Inéses_ES
dc.creatorRodríguez Yoldi, María Jesúses_ES
dc.creatorAncín Azpilicueta, Carmenes_ES
dc.date.accessioned2020-03-05T12:00:14Z
dc.date.available2020-03-05T12:00:14Z
dc.date.issued2019
dc.identifier.issn2072-6643
dc.identifier.urihttps://hdl.handle.net/2454/36417
dc.description.abstractArtichoke waste represents a huge amount of discarded material. This study presents the by‐products (bracts, exterior leaves, and stalks) of the 'Blanca de Tudela' artichoke variety as a potential source of phenolic compounds with promising antioxidant properties. Artichoke residues were subjected to different extraction processes, and the antioxidant capacity and phenolic composition of the extracts were analyzed by spectrophotometric methods and high performance liquid chromatography (HPLC) analyses, respectively. The most abundant polyphenols in artichoke waste were chlorogenic acid, luteolin‐7‐O‐rutinoside, and luteolin‐7‐O‐glucoside. Minor quantities of cynarin, luteolin, apigenin‐7‐O‐glucoside, apigenin‐7‐O‐rutinoside, and naringenin‐7‐O-glucoside were also found. The antioxidant activity of the obtained extracts determined by ABTS [2, 2’‐azinobis (3‐ethylbenzothiazoline‐6‐sulphonic acid)], DPPH (2,2‐diphenyl‐1‐pycrilhydracyl), and FRAP (Ferric Ion Reducing Antioxidant Power) was highly correlated with the total concentration of phenolic compounds. Chlorogenic acid, luteolin‐7‐O‐glucoside, and luteolin‐7‐O‐rutinoside, the most abundant compounds in 60% methanol extracts, are the components most responsible for the antioxidant activity of the artichoke waste extracts. The extract with the best antioxidant capacity was selected to assay its antioxidant potential on a model intestinal barrier. This action of the hydroxycinnamic acids on intestinal cells (Caco-2) was confirmed. In summary, artichoke waste may be considered a very interesting ingredient for food functionalization and for therapeutic purposes.en
dc.description.sponsorshipThis research was funded by the Spanish Ministry of Economy and Innovation under Grant (SAF2016-75441-R), Aragón Regional Government (B16-17R, Fondos FEDER 'otra manera de hacer Europa'.), CIBERobn under Grant (CB06/ 03/1012) of the Instituto de Salud Carlos III, and SUDOE (Redvalue, SOE1/PI/E0123).en
dc.format.extent15 p.
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherMDPIen
dc.relation.ispartofNutrients, 2019, 11 (8), 1723en
dc.rights© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectArtichoke wasteen
dc.subjectValorizationen
dc.subjectPolyphenolsen
dc.subjectAntioxidant capacityen
dc.subjectCaco-2 cellsen
dc.titlePhenolic composition of artichoke waste and its antioxidant capacity on differentiated Caco-2 cellsen
dc.typeinfo:eu-repo/semantics/articleen
dc.typeArtículo / Artikuluaes
dc.contributor.departmentCienciases_ES
dc.contributor.departmentZientziakeu
dc.contributor.departmentInstitute for Advanced Materials - INAMATes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.rights.accessRightsAcceso abierto / Sarbide irekiaes
dc.identifier.doi10.3390/nu11081723
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/1PE/SAF2016-75441-Ren
dc.relation.publisherversionhttps://doi.org/10.3390/nu11081723
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.type.versionVersión publicada / Argitaratu den bertsioaes


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© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
La licencia del ítem se describe como © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.

El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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