Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue
| dc.creator | Zapata Linares, Natalia | es_ES |
| dc.creator | Rodríguez, Saray | es_ES |
| dc.creator | Mazo, Manuel | es_ES |
| dc.creator | Abizanda, Gloria | es_ES |
| dc.creator | Barajas Vélez, Miguel Ángel | es_ES |
| dc.date.accessioned | 2020-09-22T07:53:16Z | |
| dc.date.available | 2020-09-22T07:53:16Z | |
| dc.date.issued | 2016 | |
| dc.identifier.issn | 1873-5061 | |
| dc.identifier.uri | https://hdl.handle.net/2454/38213 | |
| dc.description.abstract | In this work, mesenchymal stem cells derived from adipose tissue (ADSCs) were used for the generation of the human-induced pluripotent stem cell line G15.AO. Cell reprogramming was performed using retroviral vectors containing the Yamanaka factors, and the generated G15.AO hiPSC line showed normal karyotype, silencing of the exogenous reprogramming factors, induction of the typical pluripotency-associated markers, alkaline phosphatase enzymatic activity, and in vivo and in vitro differentiation ability to the three germ layers. | en |
| dc.description.sponsorship | This work was supported by the 'Torres Quevedo' Subprogram, Ministry of Economy and Competitiveness (PTQ-11-04777) to JRRM; the Institute of Health Carlos III (PI13/00862) to JRRM, and RETIC (RD12/0019/0031) to FP; and the Fundación Bancaria Caja Navarra (70270) to JRRM. | en |
| dc.format.extent | 4 p. | |
| dc.format.mimetype | application/pdf | en |
| dc.language.iso | eng | en |
| dc.publisher | Elsevier | en |
| dc.relation.ispartof | Stem Cell Research, 2016, 16(1), 20-23 | en |
| dc.rights | © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Mesenchymal stem cells | en |
| dc.subject | Adipose tissue | en |
| dc.subject | G15.AO. | en |
| dc.title | Generation and characterization of human iPSC line generated from mesenchymal stem cells derived from adipose tissue | en |
| dc.type | info:eu-repo/semantics/article | en |
| dc.type | Artículo / Artikulua | es |
| dc.contributor.department | Ciencias de la Salud | es_ES |
| dc.contributor.department | Osasun Zientziak | eu |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
| dc.rights.accessRights | Acceso abierto / Sarbide irekia | es |
| dc.identifier.doi | 10.1016/j.scr.2015.12.002 | |
| dc.relation.publisherversion | https://doi.org/10.1016/j.scr.2015.12.002 | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | en |
| dc.type.version | Versión publicada / Argitaratu den bertsioa | es |
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Except where otherwise noted, this item's license is described as © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.
