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Inspiratory fraction as a marker of skeletal muscle dysfunction in patients with COPD
dc.creator | Cebollero Rivas, Pilar | es_ES |
dc.creator | Zambom Ferraresi, Fabrício | es_ES |
dc.creator | Hernández, María | es_ES |
dc.creator | Hueto, Javier | es_ES |
dc.creator | Antón Olóriz, María Milagros | es_ES |
dc.date.accessioned | 2020-10-15T11:31:36Z | |
dc.date.available | 2020-10-15T11:31:36Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 2173-5115 | |
dc.identifier.uri | https://hdl.handle.net/2454/38414 | |
dc.description.abstract | Background: An inspiratory capacity to total lung capacity (IC/TLC) ratio of ≤25% has emerged as a better marker of mortality in chronic obstructive pulmonary disease (COPD) patients. The relationship among the IC/TLC ratio to lower extremity skeletal muscle function remains unknown. Methods: Thirty-five men with moderate to severe COPD were divided into those with IC/TLC ≤ 25% (n = 16) and >25% (n = 19). The subjects were tested for thigh muscle mass volume (MMT), maximal strength, power output of the lower extremities, and physical activity. Results: Total MMT in the IC/TLC < 25% group was significantly lower (413.91 ± 89.42 cm3) (p < 0.001) than in the IC/TLC > 25% group (575.20 ± 11.76 cm3). In the IC/TLC ≤ 25% group, maximal strength of the lower extremities and muscle peak power output of the lower extremities were 36---56% lower (p < 0.01) than among the patients in the IC/TLC > 25% group. Conclusion: IC/TLC ≤ 25% is associated with reduced maximal strength and peak power output of the lower extremities. IC/TLC ≤ 25% may have an important clinical relevance as an index to determine peripheral muscle dysfunction. | en |
dc.description.sponsorship | This study was conducted with the support of the Spanish Ministry of Education and Science (Plan Nacional I + D + i 2004-2007 y 2008-20011 Strategic action: 'Sport and physical education' Ref: DEP2007-73220, DEP2011-30042) and Health Sciences Department of Government of Navarre. | en |
dc.format.extent | 7 p. | |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | Elsevier | en |
dc.relation.ispartof | Revista Portuguesa de Pneumologia, 2017, 23(1), 3-9 | en |
dc.rights | © 2016 Sociedade Portuguesa de Pneumologia. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license. | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Chronic obstructive | en |
dc.subject | Pulmonary disease | en |
dc.subject | Inspiratory fraction | en |
dc.subject | Muscle mass | en |
dc.subject | Muscle strength | en |
dc.subject | Limb muscle dysfunction | en |
dc.subject | Muscle power | en |
dc.title | Inspiratory fraction as a marker of skeletal muscle dysfunction in patients with COPD | en |
dc.type | info:eu-repo/semantics/article | en |
dc.type | Artículo / Artikulua | es |
dc.contributor.department | Ciencias de la Salud | es_ES |
dc.contributor.department | Osasun Zientziak | eu |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
dc.rights.accessRights | Acceso abierto / Sarbide irekia | es |
dc.identifier.doi | 10.1016/j.rppnen.2016.07.003 | |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//DEP2011-30042-C02-01/ES/ | en |
dc.relation.publisherversion | https://doi.org/10.1016/j.rppnen.2016.07.003 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.type.version | Versión publicada / Argitaratu den bertsioa | es |
dc.contributor.funder | Gobierno de Navarra / Nafarroako Gobernua | es |