Fluid-structure simulation of a general non-contact tonometry. A required complexity?
Fecha
2018Versión
Acceso abierto / Sarbide irekia
Tipo
Artículo / Artikulua
Versión
Versión aceptada / Onetsi den bertsioa
Identificador del proyecto
Impacto
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10.1016/j.cma.2018.05.031
Resumen
Understanding corneal biomechanics is important for applications regarding refractive surgery prediction outcomes and the study of pathologies affecting the cornea itself. In this regard, non-contact tonometry (NCT) is gaining interest as a non-invasive diagnostic tool in ophthalmology, and is becoming an alternative method to characterize corneal biomechanics in vivo. In general, identification ...
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Understanding corneal biomechanics is important for applications regarding refractive surgery prediction outcomes and the study of pathologies affecting the cornea itself. In this regard, non-contact tonometry (NCT) is gaining interest as a non-invasive diagnostic tool in ophthalmology, and is becoming an alternative method to characterize corneal biomechanics in vivo. In general, identification of material parameters of the cornea from a NCT test relies on the inverse finite element method, for which an accurate and reliable modelization of the test is required. This study explores four different modeling strategies ranging from pure structural analysis up to a fluid–structure interaction model considering the air–cornea and humor–cornea interactions. The four approaches have been compared using clinical biomarkers commonly used in ophthalmology. Results from the simulations indicate the importance of considering the humors as fluids and the deformation of the cornea when determining the pressure applied by the air-jet during the test. Ignoring this two elements in the modeling lead to an overestimation of corneal displacement and therefore an overestimation of corneal stiffness when using the inverse finite element method. [--]
Materias
Corneal biomechanics,
Dynamic simulations,
Fluid-structure interaction simulations,
Non-contact tonometry
Editor
Elsevier
Publicado en
Computer Methods in Applied Mechanics and Engineering, 2018, 340, 202-215
Departamento
Universidad Pública de Navarra. Departamento de Ingeniería /
Nafarroako Unibertsitate Publikoa. Ingeniaritza Saila
Versión del editor
Entidades Financiadoras
This work was supported by the Spanish Ministry of Economy and Competitiveness (Projects DPI2014-54981-R and DPI2017-84047-R). M. A. Ariza-Gracia was supported by the Swiss Government through the ESKAS program (ESKAS-No: 2016.0194. Federal Commission for Scholarships for Foreign Students FCS, Switzerland).