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Role for physical fitness in the association between age and cognitive function in older adults: a mediation analysis of the SABE colombia study
dc.creator | Pérez Sousa, Miguel A. | es_ES |
dc.creator | Pozo Cruz, Jesús del | es_ES |
dc.creator | Olivares Sánchez-Toledo, Pedro Rufino | es_ES |
dc.creator | Cano Gutiérrez, Carlos Alberto | es_ES |
dc.creator | Izquierdo Redín, Mikel | es_ES |
dc.creator | Ramírez Vélez, Robinson | es_ES |
dc.date.accessioned | 2021-06-14T11:17:37Z | |
dc.date.available | 2021-06-14T11:17:37Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1661-7827 | |
dc.identifier.uri | https://hdl.handle.net/2454/39910 | |
dc.description.abstract | Objectives. We investigated the association between physical fitness and cognitive status. Further, we examined whether physical fitness mediates the association between cognitive functioning and aging. Design. Cross-sectional study. Setting. Urban and rural Colombian older adults. Methods. 4416 participants from the SABE study were included in the current analysis. Physical fitness was assessed with the handgrip test and the usual gait speed test. Cognitive status was evaluated through the Folstein Mini-Mental State Examination. A parallel mediation path was used to test the possible mediator role of physical fitness between aging and cognitive functioning. Results. Older adults with lower handgrip strength (HGS) were more likely to have mild-cognitive status than older adults with healthy HGS (OR = 1.53, 95% CI = 1.15; 2.02). In addition, older adults with a slower gait speed were more likely to have mild cognitive impairment (OR = 2.05, 95% CI = 1.54; 2.78). Age had an inverse relationship with cognitive function (β = -0.110, 95% CI = -0.130; -0.100) and it was also inversely associated with HGS (β = -0.003, 95% CI = -0.005; -0.002) and gait speed (β = -0.010, 95% CI = -0.011; -0.009). The indirect effects, which indicate that the effect of age on cognitive function is transmitted through mediators, showed that both gait speed (β = -0.028, 95% CI = -0.036; -0.020) and HGS (β = -0.014, 95% CI = -0.024; -0.005) were independent mediators of the detrimental effect of aging on cognitive function. Conclusions. Physical fitness mediates the effects of aging on cognitive functioning. Our findings suggest that physical activity can be a key factor to prevent cognitive deterioration during aging process. | en |
dc.description.sponsorship | The study was funded by the Ministry of Health and Social Protection of Colombia Colciencias contract No. 764 of 2013. Robinson Ramírez-Vélez training grant (ID420) as a postdoctoral research fellow with the Universidad Pública de Navarra (UPNA). | en |
dc.format.extent | 11 p. | |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | MDPI | en |
dc.relation.ispartof | International Journal of Environmental Research and Public Health, 2021, 18, 751 | en |
dc.rights | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Aging | en |
dc.subject | Cognitive status | en |
dc.subject | Physical function | en |
dc.title | Role for physical fitness in the association between age and cognitive function in older adults: a mediation analysis of the SABE colombia study | en |
dc.type | info:eu-repo/semantics/article | en |
dc.type | Artículo / Artikulua | es |
dc.contributor.department | Ciencias de la Salud | es_ES |
dc.contributor.department | Osasun Zientziak | eu |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
dc.rights.accessRights | Acceso abierto / Sarbide irekia | es |
dc.identifier.doi | 10.3390/ijerph18020751 | |
dc.relation.publisherversion | https://doi.org/10.3390/ijerph18020751 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.type.version | Versión publicada / Argitaratu den bertsioa | es |
dc.contributor.funder | Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa | es |