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dc.creatorEcheverría Morrás, Jesúses_ES
dc.creatorMoriones Jiménez, Paulaes_ES
dc.creatorGarrido Segovia, Julián Josées_ES
dc.creatorUgarte Martínez, María Doloreses_ES
dc.creatorCervera Gabalda, Laura Maríaes_ES
dc.creatorGarayo Urabayen, Enekoes_ES
dc.creatorGómez Polo, Cristinaes_ES
dc.creatorPérez de Landazábal Berganzo, José Ignacioes_ES
dc.description.abstractSuperparamagnetic iron oxide nanoparticles (MNPs) have the potential to act as heat sources in magnetic hyperthermia. The key parameter for this application is the specific absorption rate (SAR), which must be as large as possible in order to optimize the hyperthermia treatment. We applied a Plackett-Burman fractional factorial design to investigate the effect of total iron concentration, ammonia concentration, reaction temperature, sonication time and percentage of ethanol in the aqueous media on the properties of iron oxide MNPs. Characterization techniques included total iron content, Fourier Transform Infrared Spectroscopy, X-Ray Diffraction, High Resolution Transmission Electron Microscopy, and Dynamic Magnetization. The reaction pathway in the coprecipitation reaction depended on the initial Fe concentration. Samples synthesized from 0.220 mol L−1 Fe yielded magnetite and metastable precipitates of iron oxyhydroxides. An initial solution made up of 0.110 mol L−1 total Fe and either 0.90 or 1.20 mol L−1 NH3(aq) led to the formation of magnetite nanoparticles. Sonication of the reaction media promoted a phase transformation of metastable oxyhydroxides to crystalline magnetite, the development of crystallinity, and the increase of specific absorption rate under dynamic magnetization.en
dc.description.sponsorshipP. Moriones is grateful to the 'Departamento de Industria y Tecnología, Comercio y Trabajo' of the Navarre Goverment (Spain) for the fellowships granted (Ref. number 175/01/08 and 269/01/08 , respectively). L. Cervera wishes to thank the Public University of Navarre for her Ph.D contract, as part of the scheme 'Contratos Pre-doctorales adscritos a Grupos e Institutos de Investigación de la Universidad Pública de Navarra'. This work has been carried out with the financial support of the Navarra Government (project number PC017-018 AMELEC).en
dc.format.extent25 p.
dc.relation.ispartofMaterials Chemistry and Physics, Vol. 270, 15 September 2021, 124760en
dc.rights© 2021 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0en
dc.subjectFractional factorial designen
dc.subjectMagnetite nanoparticlesen
dc.subjectPhase transformationen
dc.subjectSpecific absorption rateen
dc.titleSteering the synthesis of Fe3O4 nanoparticles under sonication by using a fractional factorial designen
dc.typeArtículo / Artikuluaes
dc.contributor.departmentInstitute for Advanced Materials and Mathematics - INAMAT2es
dc.contributor.departmentEstadística, Informática y Matemáticases_ES
dc.contributor.departmentEstatistika, Informatika eta Matematikaeu
dc.rights.accessRightsAcceso embargado / Sarbidea bahitua dagoes
dc.type.versionVersión aceptada / Onetsi den bertsioaes
dc.contributor.funderUniversidad Pública de Navarra / Nafarroako Unibertsitate Publikoaes
dc.contributor.funderGobierno de Navarra / Nafarroako Gobernuaes

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© 2021 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0
Except where otherwise noted, this item's license is described as © 2021 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0

El Repositorio ha recibido la ayuda de la Fundación Española para la Ciencia y la Tecnología para la realización de actividades en el ámbito del fomento de la investigación científica de excelencia, en la Línea 2. Repositorios institucionales (convocatoria 2020-2021).
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